Welcome to this week’s Pandora Report! This issue highlights a multistate Cyclospora outbreak linked to recalled iceberg lettuce served at Taco Bell locations, updates on the continued global spread of H5N1 avian influenza from Cambodia to New Zealand, and the DHS’s new AI-enabled biological threat detection challenge under the Genesis Mission.
Taco Bell Cyclospora Outbreak Linked to Recalled Iceberg Lettuce
By Carmen Shaw, Pandora Report Managing Editor
The CDC, FDA, and public health officials are investigating a new multistate outbreak of the diarrhea-causing parasite Cyclospora, which has been linked to iceberg lettuce served at Taco Bell locations in 9 states. As of July 24, at least 1,947 confirmed illnesses and 98 hospitalizations have been reported across Illinois, Indiana, Kansas, Kentucky, Michigan, Ohio, Oklahoma, Pennsylvania, and West Virginia, with no deaths recorded. Epidemiological investigations have identified iceberg lettuce sourced from central Mexico by Taylor Farms de Mexico as the likely source of the outbreak, prompting a voluntary recall of all affected lettuce products distributed to consumers, restaurants, and retailers in at least 27 states.
Illness onset dates range from June 22 to July 20, 2026. Despite the recall, public health officials expect to see the number of confirmed cases continue to rise because it can take up to 6 weeks for laboratory testing to determine whether an illness is associated with the outbreak. The FDA continues to advise the public to avoid all products listed in Taylor Farms’ voluntary recall.
The outbreak has also temporarily affected Taco Bell’s business performance, with consumer foot traffic declining nearly 30% following public notification of the investigation. However, industry analysts expect the financial impact to be short-lived, citing the company’s rapid removal of affected lettuce from its supply chain and proactive public communications. The CDC also continues to investigate other unrelated cyclosporiasis outbreaks occurring nationwide.
Further Reading:
- “What happened in 5 previous outbreaks of foodborne illnesses at restaurant chains,” Mae Anderson and Michelle Chapman, PBS
- “Cyclospora Linked to Taylor Farms Lettuce Sent to Taco Bell,” Christina Jewett, Alice, Callahan and Caroline Hopkins Legaspi, NY Times
- “FDA still focused on Taylor Farms lettuce as Cyclospora source despite retracted test,” Yuki Noguchi, NPR
Bird Flu Claims New Territory from Cambodia to New Zealand
By Margeaux Malone, Pandora Report Associate Editor
Cambodia has confirmed its fifth human H5N1 case of the year, involving a 9-month-old girl who is currently hospitalized and receiving intensive care. No source of infection has yet been identified, though her close contacts are being given Tamiflu as a precaution. Cambodia reported 19 human cases in 2025, eight of them fatal, with most recent infections involving a reassorted strain which blends an older clade circulating since 2014 with the globally spreading 2.3.4.4b clade. Meanwhile in the US, APHIS reported a second consecutive egg-farm outbreak in Utah, bringing the 30-day national poultry toll to 1.49 million. New cattle detections in Utah and Idaho added four cases each, pushing the year’s total to 81.
Just days after confirming bird flu in a migratory bird, New Zealand detected the first infection of H5N1 in a native bird late last week. The country’s chief veterinary officer Mary van Andel says the disease is likely to become endemic within months, mirroring outcomes elsewhere in the world. Further spillover into native wildlife is probable and experts warn the consequences could be severe. In response, the Department of Conservation has begun vaccinating 300 core breeding birds across five of the country’s most endangered species, including kākāpō and takahē. Officials stress there is no food safety risk, and chicken and eggs remain safe to eat.
These developments fit a broader global picture. The dominant strain of highly pathogenic avian influenza, H5N1 clade 2.3.4.4b, has now reached every continent following the recent detections in Australia and New Zealand, closing the last geographic gap in the outbreak. Since 2020, the virus has proven unusually adept at jumping into mammals, including foxes, seals, and, unexpectedly, U.S. dairy cattle. Fortunately, human infection remains uncommon, with over 880 sporadic cases reported to the World Health Organization (WHO) since 1997 and no sustained human-to-human transmission documented. Still, scientists are watching newer, more severe genotypes and evidence of possible asymptomatic infection, which points to a virus that continues to evolve and could eventually pose a global pandemic risk.
Further Reading:
- “Cattle and human organoids reveal 2.3.4.4b H5N1 cross-species transmission potential and neuraminidase-specific neutralizing antibodies in humans,” Cun Li, et al., Nature Communications
- “Of mice, birds and men: Purdue researcher builds a simulation of how wild birds and rodents affect the spread of avian flu on farms,” Lindsey Berebitsky, Pursue University College of Agriculture
- “Rapid Funding to Explore Disease-Resistant Poultry for Avian Influenza Control,” Foundation for Food & Agriculture Research
- “WHO Member States continue negotiations on the Pathogen Access and Benefit Sharing Annex,” World Health Organization
DHS Launches AI-Driven Biological Threat Detection Challenge
The U.S. Department of Homeland Security (DHS) Science & Technology Directorate (S&T) announced a new set of national challenges – part of the “Genesis Mission” – aimed at bolstering the U.S.’ security and global leadership in critical and emerging technology. This includes an initiative to deploy AI-enabled platforms to rapidly detect, characterize, and attribute emerging biological threats to safeguard public health and the bioeconomy. By leveraging federal biological data resources, national laboratories, and cross-agency collaboration, this effort aims to shorten detection and response timelines, deter adversaries, and protect Americans from the misuse of biotechnology.
IN OTHER NEWS
- “Preparedness in Africa: How it’s evolved and what’s next,” African Health Security Index
- “Africa Health Security Index reveals progress and persistent preparedness gaps,” Science for Africa Foundation
- “OPCW supports Syrian authorities in strengthening capacity to implement the Chemical Weapons Convention,” OPCW

NEW: DC Biosecurity Happy Hour
Join the DC Biosecurity Happy Hour, an informal event for biosecurity enthusiasts in DC to get to know each other outside of Zoom calls and talk about new ideas in the space.
This event will take place on Tuesday, July 28, from 6:30 PM-8:30 PM ET. Learn more and register here.
NEW: Rising Temps, Rising Risks: Infectious Disease in the 2026 El Niño Year
From the Pandemic Center: “Climate variability, including El Niño-driven shifts in temperature and rainfall, is reshaping infectious disease risks by altering the environments where pathogens and vectors thrive. This year is progressing towards a historically severe El Niño event — a naturally occurring climate pattern characterized by the warming of surface waters in the central and eastern Pacific Ocean.
What impact will this compounding climate event have on disease prevalence, and which regions are most vulnerable? In this Pandemic Center webinar, we will convene an expert panel to discuss these questions and more.”
This webinar will take place on July 31 at 12:00 PM ET. Learn more and register here.
Data and Situational Awareness for Medical and Public Health Preparedness and Response: A Workshop Series
From the National Academies: “The Forum on Medical and Public Health Preparedness for Disasters and Emergencies workshop series will explore how medical, public health, emergency management, and critical infrastructure data are collected, integrated, analyzed, and translated into real-time information to support timely, coordinated decision-making before, during, and after disasters and emergencies.”
This workshop series will take place on July 21, July 28, and September 23. Learn more and register here.
Tracking Health Security Progress and Building Resilience in Africa – A Webinar
From the Nuclear Threat Initiative (NTI): “The world is shifting from a period of urgent health actions to one of vast growing neglect, even as biological threats continue to rise. Against this backdrop, the 2026 Africa Health Security Index shows great progress has been made across the continent – but substantial gaps remain.
Join NTI, the Brown University Pandemic Center, Economist Enterprise, and the Science for Africa Foundation for a discussion of the findings and recommendations of the 2026 Africa Health Security (AHS) Index, an independent assessment of health security capacities in Africa.
This webinar will convene global experts and policymakers to discuss how the AHS Index can shape policy decision-making and drive meaningful action to strengthen health security capacities and improve preparedness for future epidemics and pandemics.”
This virtual event will take place on July 29 from 8:30 AM-10:00 AM ET (3:30-5:00 PM EAT). Learn more and register here.
Preparing for a Future of AI-Enabled Biology – A Workshop
From the National Academy of Medicine (NAM): “Artificial intelligence (AI) is transforming the life sciences, including how researchers study biology, develop vaccines and treatments, and detect disease outbreaks. While these advances could improve public health and preparedness, they also raise important questions about safety, security, and the possibility of misuse.”
This event will take place on August 11-12. Learn more and register here.
Ninth Session of the Working Group on the Strengthening of the Biological Weapons Convention
From the United Nations Office for Disarmament Affairs (UNODA): “We will convene the Ninth Session of the Working Group on the Strengthening of the Biological Weapons Convention (BWC). Chaired by Ambassador Frederico S. Duque Estrada Meyer of Brazil, the meeting will bring together State Parties, international organizations, academic institutions, and civil society representatives to continue discussions on strengthening the Convention and advancing efforts to address biological threats. Public sessions will be webcast through UN Web TV, and side events are expected throughout the week.
This event will take place from August 17-21 at the Palais des Nations in Geneva, Switzerland. Learn more and register by July 31st here.
Biosecurity Simulation Exercise (BSX 2026): Laboratory Incidents & Deliberate Biothreats
From the Asia Centre for Health Security: “This table-top simulation exercise aims to enhance inter-sectoral and inter-disciplinary preparedness for laboratory biosafety and biosecurity (LBB) and deliberate biothreat events (DBE). Through lectures, discussions, and structured, scenario-driven exercises, participants will explore decision-making to detect, risk-assess, and manage high-consequence biological incidents under conditions of incomplete information and unfolding events. Participants will collaborate in teams, building on expert perspectives to address issues in surveillance, diagnostics, public health response, security assessment, and risk communication.”
This in-person event will take place from August 27-28. Learn more and register here.
Training Course on ‘Biotechnology Innovation and Biosecurity’
From the International Centre for Genetic Engineering and Biotechnology (ICGEB) and the Biological Weapons Convention Implementation Support Unit: “This training focuses on strengthening capacities in biosecurity, biosafety, and biological risk management in the context of rapid advances in biotechnology with an integrated, interdisciplinary approach to manage biothreats at the intersection of humans, animals, plants and the environment. It addresses the governance, technical, and operational dimensions of preventing, detecting, and responding to biological threats, while promoting responsible and peaceful scientific research and innovation in accordance with article X of the Biological Weapons Convention (BWC).”
This in-person event will be held from October 12-16 in New Delhi, India. Learn more and apply here.
Biomanufacturing for Defense & Security Summit
From Diversified Solutions Incorporated (DSI Groups): “This event will bring together senior thought leaders and stakeholders from across DoW, Military Research Labs, Federal Government, Commercial Industry, & Academia to discuss how each are advancing biomanufacturing to enhance national security objectives, produce critical materials for defense applications, and strengthen the overall U.S. bioindustrial manufacturing base. Biomanufacturing is crucial for U.S. national security because it enables domestic production of critical materials, medicines, and defense supplies, reducing reliance on foreign adversaries, which in turn creates resilient supply chains for the military and economy.”
This event will take place from October 27-28 at the National Harbor, MD. Learn more and register here.

WHO Internship Programme
From WHO: “A competent and dynamic health workforce at the heart of each health system is essential to advance global health goals. Countries need a pool of health professionals trained and exposed to the systems and processes in the health sector and who understand how stakeholders interact within the international health arena. WHO’s Internship Programme offers a wide range of opportunities for students and recent graduates to gain insight into the technical and administrative programmes of WHO and enrich their knowledge and experience in various areas, thereby contributing to the advancement of public health.”
Learn more and apply here.
OpenAI Bio Bug Bounty Program
From OpenAI: “As part of our ongoing efforts to strengthen our safeguards for advanced AI capabilities in biology, we’re evolving our GPT‑5.5 Bio Bug Bounty to become an ongoing private program—the OpenAI Bio Bounty Program. The program will remain focused on universal jailbreaks that can defeat our predefined biosafety challenge against OpenAI’s frontier models, starting with GPT‑5.6 and going forward. The reward for a universal jailbreak for the OpenAI Bio Bounty Program has been raised from $25,000 to $50,000 for both GPT‑5.6 and GPT‑5.5. Smaller awards may be granted for partial wins at our discretion.”
Learn more and submit your application here.
Disarmament and non-proliferation of WMD – Training Program
From Asser Institute and OPCW: “By 2026, pressure on the international arms control system has reached a point few experts anticipated would arrive so quickly, driven largely by intense geopolitical fragmentation. There is a critical need for professionals who possess the legal, technical, and diplomatic expertise to navigate these modern complexities. This intensive five-day training provides a comprehensive, practical overview of the international non-proliferation and disarmament framework.”
This program will take place from October 26-30 in The Hague, the Netherlands. Learn more and register here.





