Welcome to this week’s Pandora Report! This issue highlights the growing public health risks posed by vaccine hesitancy, highlighted by the ongoing measles outbreaks and shifting federal policies that may undermine trust in scientific institutions. It also spotlights global leadership in biodefense, with a GMU PhD student selected as the U.S. Head Delegate to Y20 USA 2026.
Thinking about Getting a Master’s in Biodefense?
The George Mason University Schar School of Policy and Government will host an upcoming Master’s in Biodefense information session:
The Return of Measles: Vaccine Hesitancy and the Erosion of U.S. Public Health
By Cameron Daniel Benton
As globalization increases and societies becomes more interconnected, developing and maintaining strong public health measures is more vital than ever. However, previously eradicated diseases are reemerging in the United States due to vaccine hesitancy and shifting policies under the current presidential administration. The 2025 measles outbreak in West Texas serves as a warning sign of what may follow if the nation continues to neglect preventable diseases. The 2025 West Texas measles outbreak has spread to neighboring states, Mexico, and Canada1 and represents a risk to immunocompromised individuals and, in rare cases, to vaccinated individuals through breakthrough infections.2
The Trump Administration is actively pivoting away from established, scientific-based evidence and towards dubious alternatives. This shift has damaging implications for local communities that rely on scientific guidance from medical professionals. For example, during the 2025 measles outbreak, Health and Human Services Secretary Robert F. Kennedy Jr., a known vaccine skeptic, initially downplayed the severity of the crisis, misleadingly suggested that vitamin A prevents measles, and directed the Centers for Disease Control and Prevention (CDC) to distribute additional vitamin A to the Texas Department of Health.3 As a result, some children were hospitalized with both vitamin A toxicity and measles.4 Although Secretary Kennedy later admitted in a Fox News op-ed that the MMR vaccine is “crucial to avoiding potentially deadly disease,”5 the conflicting messages from senior government officials contribute to ongoing vaccine hesitancy.
Vaccine hesitancy is one of several factors for parents to forego life-saving vaccines for easily preventable diseases such as measles. A May 2023 study highlights various social factors, such as misinformation, low trust, and limited perception of personal risk and susceptibility to measles,6 as major drivers of the decline in MMR vaccination rates. The Atlantic interviewed Peter, whose daughter passed away during the 2025 outbreak, which was the first measles-related death in the United States in a decade. Peter remarked that “[measles] is not so new for us” and “everybody has it” since his grandparents and parents had it. He also said that “the vaccination has stuff that we don’t trust.”7 As the vaccination rates and trust in vaccines decrease, children will become more susceptible to otherwise preventable diseases.
Meanwhile, Dr. Ralph Abraham, the CDC’s Principal Deputy Director, recently said that the uptick in measles cases is “just the cost of doing business with our borders being somewhat porous for global and international travel.” He also emphasized the “personal freedom” of communities that choose to remain unvaccinated.1 This attitude towards measles demonstrates a shift in focus from robust, proactive public health measures to a more reactive approach. Trust in the government will likely decline as the American public perceives low prioritization of preventable disease outbreaks. Continued measles outbreaks will likely disrupt childhood education, become more common throughout the country, and become deadlier.
The current administration is reversing policy on vaccine safety through more than just public messaging, which is reflected in the data the CDC tracks in the United States. A recent study tracked how certain CDC databases had “unexplained pauses” in their updates. As of October 28th, 2025, 38 (46%) of these databases were paused, and of these, 33 (87%) were related to vaccine monitoring. 34 of the paused databases were not updated within 6 months of the study. These long pauses jeopardize the evidence that public health officials, scientists, government officials, and medical professionals use when evaluating information. The lack of transparency around the pauses further contributes to the decline in public trust.
In 2025, Secretary Kennedy unilaterally fired the entire board of the CDC’s Advisory Committee on Immunization Practices (ACIP)8 and reduced the recommended childhood vaccine schedule from 17 to 11 vaccines, citing concerns that children receive “too many” vaccines.9 These actions align with the administration’s overall indifference towards vaccines and public health. In response, 28 states rejected the revised guidelines and continue to follow recommendations from the American Academy of Pediatrics.10 As parents continue to forgo the MMR vaccine, we may someday see the return of mumps and rubella in the United States. Conflicting vaccine information from two respected scientific agencies will very likely deepen the public’s distrust regarding new recommendations.
Secretary Kennedy’s restructuring and dismantling efforts of various health departments do not exist in a vacuum and align with President Trump’s transactional view of domestic and international politics. On January 22, 2026, the Trump Administration recently completed the United States’ withdrawal from the World Health Organization (WHO). This withdrawal happened exactly one year after President Trump signed an executive order to initiate the withdrawal process.11 While the long-term effects remain to be seen, the WHO has now lost major funding for various initiatives to combat and monitor various diseases.
These new public health policies also have negative financial and economic impacts during outbreaks. When children are sick with measles, parents often need to take time off work, pull children out of school, take them to the hospital or urgent care, spend money on medicine, and their jobs lose productivity. State and federal officials also spend valuable resources managing outbreaks, establishing contact tracing, utilizing diagnostics, and initiating emergency responses.12 Researchers estimate the 2019 measles outbreak in Washington state, for example, cost approximately $3.4 million for 71 measles cases, illustrating how reactive response efforts to preventable diseases generate disproportionate financial strain.1
South Carolina’s Department of Public Health has reported 847 cases of measles in Spartanburg County as of January 30th,1 and Virginia confirmed 4 cases as of February 1, 2026.13 As measles continues to spread throughout the country, the Trump Administration can take steps to ensure the public remains healthy, children are protected, and the economy remains stable. The administration, state, and local government officials should invest in measles-related diagnostic kits, training for healthcare workers, and temporarily increase MMR vaccine production. President Trump can also sign new executive orders directing artificial intelligence (AI) companies to shift efforts toward medical research and pharmaceutical production. This will ensure Americans remain healthy, make the U.S. competitive in global markets, and stimulate the economy with positive, tangible, and healthy outcomes.
Further Reading:
1 “Top CDC Official Says Measles Surge Is the ‘Cost of Doing Business’,” Neurology Advisor
2 “Utah Measles Outbreak Response,” Utah Department of Health and Human Services
3 “Measles, Vitamin A, and RFK Jr.’s About-Face,” Christopher Labos, McGill Office for Science and Society
4 “West Texas children treated for vitamin A toxicity as medical disinformation spreads alongside measles outbreak” University of Nebraska Medical Center
5 “ROBERT F. KENNEDY JR.: Measles outbreak is call to action for all of us,” Robert F. Kennedy, Jr., Fox News
6 “Why Parents Say No to Having Their Children Vaccinated against Measles: A Systematic Review of the Social Determinants of Parental Perceptions on MMR Vaccine Hesitancy,” Novilla et al., 2023
7 “His Daughter Was America’s First Measles Death in a Decade,” Tom Bartlett, The Atlantic
8 “Members of CDC vaccine panel ousted by RFK Jr. say committee has ‘lost credibility’,” Mary Kekatos, ABC News
9 “HHS announces unprecedented overhaul of US childhood vaccine schedule,” Stephanie Soucheray and Liz Szabo, CIDRAP
10 “28 states reject the CDC’s new childhood vaccine schedule, KFF finds,” Austin Littrell, Medical Economics
11 “United States Completes WHO Withdrawal,” U.S. Department of Health and Human Services
12 “The Economic Impact of the Ongoing Measles Outbreak,” Johns Hopkins Bloomberg School of Public Health
13 “Societal Costs of a Measles Outbreak,” Pike et al., 2022
14 “2025 Measles Outbreak,” South Carolina Department of Public Health
15 “About Measles,” Virginia Department of Health
GMU Biodefense PhD Student Selected as U.S. Head Delegate to Y20 USA 2026

George Mason University continues to foster global leadership and policy innovation through its research community. Carmen Shaw, a PhD student in Biodefense, has been selected as the U.S. Head Delegate to the G20 Youth Summit (Y20) in Washington DC, United States in August 2026. She will help lead youth engagement on food security and global health alongside her international peers to develop a final communiqué report that will be delivered to G20 leaders. This recognition highlights GMU’s role in preparing the next generation of leaders addressing complex global challenges.
IN OTHER NEWS
Public Health, Pandemic Preparedness, and Biosecurity
- “What can biosecurity learn from cybersecurity? A lot.” Filippa Lentzos, Bulletin of the Atomic Scientists
- “WHO Member States agree to extend negotiations on key annex to the Pandemic Agreement,” World Health Organization
- “INTERCEPTOR expands global network with five new partners to boost pandemic preparedness,” Interceptor
- “The Horrors That Could Lie Ahead if Vaccines Vanish,” Lucas Waldron and Patricia Callahan, ProPublica
Health Systems Disruptions & Scientific Infrastructure
- “C.D.C. Pauses Testing for Rabies and Pox Viruses,” Apoorva Mandavilli, NY Times
- “Sources: White House to propose 20 percent cut to NIH funding,” Ariel Cohen, Roll Call
- “Iran Faces Major Assault as Historic Medical Research Hub Severely Damaged,” Daisy Moraa, The Kenya Times
Conflict, Military, and Biochemical Threats
- “Italian Christmas meal tragedy turns into murder inquiry,” Laura Gozzi, BBC
- “Army wants better, faster defenses against chemical and biological threats,” Nick Wakeman, Washington Technology
- “Water wars: the final escalation?” Verity Bowman, The Telegraph
- “Israel Strikes Tehran Pharmaceutical Plant, Claiming Military Link,” Parin Behrooz and Ephrat Livni, NY Times

NEW: 2026 Preparedness Summit, “Protecting Our Communities: State and Local Preparedness in Action.”
From the Preparedness Summit: “This event spotlights the need for increased self-reliance on state and local partnerships amid a changing federal policy and budget landscape. This conference will be the beginning of an ongoing national conversation focusing on the evolution of the public health preparedness system.”
This virtual event will be held from April 13-16. Learn more and register here.
Consortium of Universities for Global Health (CUGH) 2026 Pre-Conference Workshop: Communications Skills that Transform Science into Action
From CUGH: “In today’s complex information landscape, great research needs more than publication—it requires communication. This interactive workshop, led by the CUGH Research Committee, the Pulitzer Center, and Global Health NOW, equips global health scientists, researchers, and students with practical skills to amplify their work and translate evidence into impact. Panel discussions among leading journalists, communicators, and academics will deepen participants’ understanding of current communication challenges. Workshops will teach attendees how to craft clear, compelling messages targeting policymakers, practitioners, and the public via op-eds, media interviews, social media, podcasts, newsletters, etc. Hands-on exercises, immediate feedback, and real-world examples will boost attendees’ ability to influence global health dialogue, policy, and action. Transform your research into a story that matters.”
This event will be held on April 9 from 9:00 AM – 4:00 PM ET. Learn more and register here.
Game Changers: Cures for 21st Century Biological Threats
From the Bipartisan Commission on Biodefense at the Atlantic Council: “The Commission will host its latest meeting, focused on assessing strategies for strengthening biodefense science and technology. They will conceptualize the successes of and challenges facing biodefense technology innovators in an ever-changing threat environment.
Biotechnology has accelerated at a rapid pace, driven in part by federal investment and policy. Advances in biological sciences create new opportunities for addressing biological events, and the public and private sectors at all levels have a role to play in bolstering these efforts. This meeting of the Commission will discuss the biological threat to food and agriculture, and the international perspective on the threat. The discussions will also touch upon the state of biotechnology innovation and federal regulation, research and development activities.”
This event will be hybrid (in-person and online) and will be held on Friday, April 10, at 9:00 AM ET. Learn more and register here.
CBRNe Convergence Canada 2026
CBRNe World is hosting its fourth CBRNe Convergence Canada event this year in Toronto! This event will focus on a range of topical issues, including responding to potential CBRN incidents in the High North, response to terrorist attacks at major sporting events, and presentations on Canadian response capabilities, and the largest CBRN/Hazmat exhibition in Canada.
This event will take place April 13-15 at the Double Tree by Hilton Hotel, Toronto Downtown. Learn more here, and stay tuned for forthcoming information about CBRNe Convergence this November in Knoxville, TN!
International Conference CBRNe Research & Innovation
From CBRNE: “The last 40 years have demonstrated that both military and civilian populations could be exposed to highly hazardous CBRNE agents following conflicts, natural outbreaks and disasters, industrial incidents or terrorist attacks. Worldwide, researchers, responders and industrial capacities have been commited to provide adapted response to these challenges. The CBRNE Research & Innovation Conference includes workshops and demonstrations of innovative materials, technologies and procedures, according to the following themes: Detection (identification), Protection (decontamination, medical countermeasures), and risk & crisis management.
This event will take place in Arcachon, France, from May 19 – 21, 2026. Learn more and RSVP here.
GHS 2026
From GHS: “We’re excited to officially announce that the 4th Global Health Security Conference (GHS2026) will be held in Kuala Lumpur on the 9 – 12 June, 2026!”
“Building on the incredible momentum of GHS2024 in Sydney, we look forward to bringing together the global health security community once again – this time in one of Southeast Asia’s most vibrant and dynamic cities.”
“Registration and Call for Abstracts are now live!”
Learn more, submit abstracts, and register here.
Biosecurity Simulation Exercise (BSX 2026): Laboratory Incidents & Deliberate Biothreats
From the Asia Centre for Health Security: “This table-top simulation exercise aims to enhance inter-sectoral and inter-disciplinary preparedness for laboratory biosafety and biosecurity (LBB) and deliberate biothreat events (DBE). Through lectures, discussions, and structured, scenario-driven exercises, participants will explore decision-making to detect, risk-assess, and manage high-consequence biological incidents under conditions of incomplete information and unfolding events. Participants will collaborate in teams, building on expert perspectives to address issues in surveillance, diagnostics, public health response, security assessment, and risk communication.”
This in-person event will be held from August 27-28. Learn more and register here.

NEW: The Global Congress on Chemical Security and Emerging Threats – Call for Abstracts
From INTERPOL: “The 6th Plenary Meeting of the Global Congress on Chemical Security & Emerging Threats will be in Panama City from 21-24 Sept 2026. The event brings together governments, industry, academia, & international orgs to strengthen chem security through collaboration & action. By providing a platform for multi-sector global cooperation and partnership, the Global Congress enables members to build relationships, exchange expertise, share important information on emerging threats and innovative best practices, and enhance capabilities.”
The call for abstracts is now open, and the applications are due by May 15. Learn more about the conference here and apply here.
Bio-Leadership Summit (BLISS) – Submit your Nominations
From the Hoover Institution: “Bio-Strategies & Leadership at the Hoover Institution will convene ~300 action-oriented leaders at Stanford for the inaugural Bio Leadership Summit, a one-day event designed to elevate biotechnology culturally and politically, and to speak frankly regarding what biotech leadership looks like across the most important domains of strategic impact. We are looking for leaders—up and coming or established, with or without a biotechnology background—who have a track record of turning ideas into outcomes to participate.”
The summit will occur on April 14. Learn more and submit your nominations here.
Council on Strategic Risks Mid-Career Biodefense Bootcamp Fellowship – Call for Applications
From CSR: “The Council on Strategic Risks (CSR) is announcing an open call for applications for our 2026 Mid-Career Biodefense Bootcamp, a unique fellowship opportunity that we will host in the United States.
Whether arising naturally, by accident, or through a deliberate effort to weaponize infectious diseases, biological threats pose grave risks to international security and stability. This is a highly dynamic time for biological risks, as we are witnessing an incredible pace of technological change against the backdrop of a shifting, dangerous global security landscape. Biological risks are as concerning as ever—and we are entering a new era in terms of the tools and approaches available to mitigate them. Informed by the unique experiences of its staff and years of collaboration across its expert networks, CSR’s work related to biological threats ties to a bold vision: making biological weapons the first category of weapons of mass destruction to be rendered obsolete in terms of their mass-destruction potential; and preventing any future infectious disease outbreaks from reaching pandemic scale. To achieve this goal, CSR is continuing to develop and cultivate creative solutions to address biological threats, including ways countries can effectively prepare for them.”
Applications are due on April 24. Learn more and apply here.
Strengthening Biosecurity & Pandemic Preparedness Through Intergenerational Dialogue – Applications Open
From the Nuclear Threat Initiative (NTI): “As breakthroughs in artificial intelligence (AI) and biotechnology outpace global governance, the Nuclear Threat Initiative (NTI) and The Elders are launching a new intergenerational initiative to generate the ideas and leadership needed for a safer future against biological threats.
NTI and The Elders are pleased to invite applications for a high-level Intergenerational Dialogue that will focus on emerging technologies, pandemic preparedness, prevention, and response (PPR), and global biosecurity governance. This dialogue will bring together early career professionals with senior global leaders to explore how technological innovation can strengthen health security while reducing catastrophic biological risks.
Building on NTI’s Next Generation for Biosecurity project and The Elders’ leadership on pandemic prevention and global cooperation, this initiative will foster candid exchange across generations, elevate diverse perspectives, and generate forward-looking ideas to inform global advocacy and policy priorities.”
The application deadline is Sunday, May 3 at 11:59 PM ET. Learn more and apply here.
Bio-attribution Challenge
From DARPA: “Translate your bio-attribution research into national security impact. In an era of unprecedented biological data generation, the ability to rapidly determine the origin of a biological event — whether natural, accidental, or intentional — is a critical component of national security and public health. To meet the challenge of finding the “needle in a haystack” within this data deluge, the Defense Advanced Research Projects Agency (DARPA) has launched the Bio-Attribution Challenge.
This virtual competition calls on innovators to develop a new generation of tools capable of analyzing petabyte-scale datasets in near real-time, far exceeding the capacity of current systems. The goal is to revolutionize how we identify and trace the source of biological sequences, ensuring a faster, more effective response to potential threats. Register for virtual competition to win a share of $180,000 in Prizes.”
The deadline to register is June 15. Learn more and register here.







