Pandora Report 9.11.2026: 25 Years After 9/11 – Biodefense Then, Now, and What Comes Next

Welcome to this week’s Pandora Report! This issue examines the evolution of U.S. biodefense 25 years after 9/11, the continuing debate over H5N1 vaccination, and the emerging applications of AI for detecting biological threats.


Join the Chemical Weapons Convention Coalition and Arms Control Association for a virtual briefing, “Syria’s Chemical Weapons Legacy: Current Issues and Challenges,” on September 16 from 11:00 AM-12:30 PM ET. The briefing will examine Syria’s ongoing efforts to address the chemical weapons legacy of the Assad regime. Gregory Koblentz, Director of GMU’s Biodefense Program, will moderate the discussion.



25 Years After 9/11: Remembering and Reflecting on the Evolution of Biodefense

By Carmen Shaw, Pandora Report Managing Editor

On the 25th anniversary of the September 11, 2001, attacks, the Pandora Report reflects on the lives lost, the attacks’ enduring impact, and how 9/11 and the subsequent anthrax attacks reshaped U.S. approaches to biodefense and national security. Source: Pexels.

Twenty-five years ago today, the United States experienced one of the most consequential terrorist attacks in its history. On September 11, 2001, nearly 3,000 people were killed in New York City, at the Pentagon in Arlington, Virginia, and in Pennsylvania. Thousands more were injured, and countless families, communities, and first responders have continued to live with the consequences of that day.

For the Pandora Report, September 11 offers an opportunity for both remembrance and reflection on how the attacks transformed the way the United States understands and prepares for modern security threats.

In the weeks following the attacks, letters laced with Bacillus anthracis spores were mailed to news media organizations and U.S. Senate offices, resulting in 22 cases of anthrax and five deaths. The 2001 anthrax attacks radically changed U.S. biosecurity and public health preparedness, including through the creation of the Federal Select Agent Program (FSAP) to regulate and oversee the use of dangerous biological agents that pose a threat to public, animal, or plant health.

Together, the September 11 and the subsequent anthrax attacks helped accelerate the development of the modern U.S. biodefense enterprise. They also triggered a broader transformation in homeland security, including the creation of the Transportation Security Administration (TSA) and the Department of Homeland Security (DHS), as well as the passage of the USA PATRIOT Act, which expanded government surveillance and law enforcement powers to prevent future terrorism.

Twenty-five years later, the threat landscape has continued to evolve. Emerging infectious diseases, advances in biotechnology, synthetic biology, artificial intelligence (AI), and the possibility of biological misuse present challenges that require many of the same capabilities that became priorities after 2001: early warning and biosurveillance, scientific expertise, interagency information sharing and coordination, and the ability to respond quickly when the nature of a threat is uncertain.

At its core, 9/11 is about the people who were killed and the families, first responders, service members, public servants, and communities forever changed by that day.

We remember those who were lost, honor those who responded, and reflect on our shared responsibility to build a safer and more resilient future.

Bird Flu Season Returns, So Does the Vaccination Debate

By Margeaux Malone, Pandora Report Associate Editor 

As the northern hemisphere begins to head into autumn, Bulgaria and France each confirmed their first H5N1 highly pathogenic avian influenza (HPAI) outbreaks of the season. France’s case was notable because the affected ducks had already been vaccinated under the country’s mandatory H5N1 immunization program. This recent outbreak in France, alongside two articles published this week, reignites the question of the role of vaccination in H5N1 control and prevention efforts.

The first article, published in Poultry Science and Management by researchers in Egypt, tested six commercial H5 vaccines against currently circulating clade 2.3.4.4b H5N1 and H5N8 strains in chickens. Most vaccines prevented death, with 75-100% survival compared to 100% mortality in the unvaccinated control group. However, none stopped birds from shedding virus for up to a week after exposure, and vaccines built on older or more distantly matched strains produced weaker protection. The authors concluded vaccination reduces mortality but, without regularly updated strains, still permits silent spread. Furthermore, use of suboptimal vaccines or inadequate vaccination programs may contribute to the selection of mutant strains through immune pressure, potentially reducing vaccine effectiveness.

The second, a Viewpoint article in the Journal of the American Veterinary Medical Association, asks why the US still does not vaccinate its poultry against H5 HPAI at all? The authors, from the University of Minnesota’s Secure Food Systems team, note that while effective vaccines, risk-mitigation frameworks, and risk-based surveillance systems already exist in the US, trade is the biggest issue. Vaccination plans could alter trade agreements, putting the US poultry meat and egg trade surplus at risk. There are also fears that products from vaccinated flocks could carry undetected, asymptomatic infections, leading to import restrictions. Traceability is another major hurdle. A vaccination program would require tracking which flocks were vaccinated and following their products through the supply chain. The poultry industry already does this for other purposes, like antibiotic-free labeling, but adapting those systems to a centralized, auditable, and validated process that trading partners will accept remains a barrier.

Vaccination is a valuable tool, but it isn’t a complete solution. Vaccinated flocks can still become infected and continue shedding virus, particularly when vaccine strains fall out of step with circulating field viruses. Meanwhile, in places where vaccine adoption has stalled, the holdup often has less to do with vaccine efficacy and more to do with economic concerns. Closing the gap on H5N1 will require progress on both fronts. Vaccine programs need to become more adaptive and be backed by surveillance and policy frameworks that give countries the confidence to actually use them.

Further Reading: 


DHS S&T Launches “Ready, Set… ID The Biothreat” Prize Challenge to Advance AI-Assisted Biodefense

The U.S. Department of Homeland Security Science and Technology Directorate (S&T) has launched “Ready, Set…ID the Biothreat,” a prize challenge seeking AI-assisted algorithms for biodefense. The challenge is seeking innovative artificial intelligence approaches to help identify biological threats in complex environmental data. Eligible U.S. innovators, companies, academics, laboratories, and other technology developers over the age of 18 who are U.S. citizens or legal permanent residents can compete for up to $999,990 in prizes, with submissions due October 14, 2026. To learn more about the Challenge, visit the website here.


IN OTHER NEWS

Chemical Weapons & WMD Proliferation

AI & Biosecurity

U.S. Biodefense Policy and Institution & Funding

Global Health Security

NEW: America’s Ebola Response: Travel Restrictions, Quarantines, and Citizen Rights

From The Pandemic Center: “As part of the U.S. response to the still-ongoing Ebola outbreak in the Democratic Republic of Congo (DRC), the Trump administration took unprecedented steps to block American citizens in the DRC from returning to the U.S., placing them on a “do-not-board” list until they spend at least 21 days in a third country. These travel restrictions, the quarantining and detainment of US citizens, and the construction of the facility in Kenya have spurred ethical concerns and even legal challenges.”

This webinar will take place on Friday, September 18 at 12:00 PM ET. Learn more and register here.

Exponential AI and Biotech Growth: Translating Technical to Policy – Workshop

From AI for SynBio: “The continued acceleration of agentic artificial intelligence (AI), Biological Design Tools (BDTs), and Biological AI Models (BAIMs) has transformed the technological landscape, enabling tremendous benefits and potential misuse that could massively impact national security, defense, health, and economy. Mitigating this risk will require collaboration across Government, Industry, and Academia with both technical and policy focuses. Significant effort, especially at the federal level, has been made to raise awareness of this challenge, yet additional discussion is necessary to keep pace with the ever-evolving speed of this global technology.’

This workshop will take place from September 15-17 at the Hopkins Bloomberg Center in Washington, DC. Learn more and register here.

Bioeconomy Summit

The Bioeconomy Summit, hosted by TechConnect, will bring together industry leaders, investors, federal officials, and experts to examine how the United States can strengthen and scale its bioeconomy. The summit will focus on aligning capital, policy, infrastructure, procurement, and industrial capacity; addressing vulnerabilities in biomanufacturing supply chains; and accelerating the deployment of bioindustrial technologies.

The summit will take place on Monday-Tuesday, September 21-22, at the National Harbor in Maryland. Learn more and register here.

Science of Evaluation of Artificial Intelligence for Life Sciences and Biotechnology Conference

From the National Academies: “This meeting brings together researchers and practitioners across various fields to define the emerging scientific method for artificial intelligence, focusing on benchmarks, leaderboards, challenges, and the evidence needed to trust systems that reason, act, discover, and operate in high-stakes domains, including the life sciences and biotechnology sectors.”

This conference will take place on Tuesday-Wednesday, September 22-23. Learn more and register here.

Data and Situational Awareness for Medical and Public Health Preparedness and Response: A Workshop Series

From the National Academies: “The Forum on Medical and Public Health Preparedness for Disasters and Emergencies workshop series will explore how medical, public health, emergency management, and critical infrastructure data are collected, integrated, analyzed, and translated into real-time information to support timely, coordinated decision-making before, during, and after disasters and emergencies.”

This workshop series will take place on September 23. Learn more and register here.

The Second Bio-Responsibility Policy Lecture: “From Lab Safety to Bio-Responsibility: Building the Human Infrastructure for Safe and Secure Science.”

From organizers: “Advances in the life sciences are creating new opportunities for health, biotechnology, and economic development while also presenting increasingly complex biosafety and biosecurity challenges. The lecture will examine how institutions can develop practical, risk-based biorisk management systems, with a focus on the trained professionals and institutional capacity needed to translate policy into practice. It will also explore approaches to expanding biorisk management capacity through scalable training, competency development, and institutional support, including in resource-constrained settings.”

The virtual lecture will take place on Thursday, September 24, 8:00 AM – 9:15 AM ET. Learn more and register here.

International Bio-Responsibility Conference 2027

Organized under the Bio-Responsibility Initiative at the Centre for Society and Policy (CSP), the conference brings together people to advance dialogue, build partnerships, and promote safe, secure, and responsible life science research, development, and innovation. The conference will host experts, policymakers, and practitioners around the world to discuss emerging biological risks and ways to strengthen responsible governance.

The deadline to register is September 30. Learn more and register here.

Training Course on ‘Biotechnology Innovation and Biosecurity’

From the International Centre for Genetic Engineering and Biotechnology (ICGEB) and the Biological Weapons Convention Implementation Support Unit: “This training focuses on strengthening capacities in biosecurity, biosafety, and biological risk management in the context of rapid advances in biotechnology with an integrated, interdisciplinary approach to manage biothreats at the intersection of humans, animals, plants and the environment. It addresses the governance, technical, and operational dimensions of preventing, detecting, and responding to biological threats, while promoting responsible and peaceful scientific research and innovation in accordance with article X of the Biological Weapons Convention (BWC).”

This in-person event will be held from October 12-16 in New Delhi, India. Learn more and apply here.

Biomanufacturing for Defense & Security Summit

From Diversified Solutions Incorporated (DSI Groups): “This event will bring together senior thought leaders and stakeholders from across DoW, Military Research Labs, Federal Government, Commercial Industry, & Academia to discuss how each are advancing biomanufacturing to enhance national security objectives, produce critical materials for defense applications, and strengthen the overall U.S. bioindustrial manufacturing base. Biomanufacturing is crucial for U.S. national security because it enables domestic production of critical materials, medicines, and defense supplies, reducing reliance on foreign adversaries, which in turn creates resilient supply chains for the military and economy.”

This event will take place from October 27-28 at the National Harbor, MD. Learn more and register here.

Frontiers in Synthetic Biology: SpudCells, Mirror Life and Societal Implications

From the Consortium on Law and Values: “Advances in cell engineering and synthetic biology offer enormous potential benefits, while raising ethical and policy issues. SpudCell, the first synthetic cell that can grow and reproduce, built from non-living chemicals, was developed by a team at the University of Minnesota. Scientists have cautioned against creating organisms with molecules that are mirror images of the biological components of known life, as existing organisms would have no immune defenses. Join three experts on synthetic biology, biosecurity, and bioethics to explore how to realize the promise of synthetic biology while controlling potential risks.”

This webinar will take place on Thursday, October 29, at 3:00 PM ET. Learn more and register here.

Pandora Report 9.04.2026: Biodefense Goes Local, H5N1 Hits Mink Farms, and AI Reshapes Bioweapons Risk

Welcome to this week’s Pandora Report! This issue examines the growing importance of local capacity in biodefense, the detection of H5N1 on a U.S. mink farm, and emerging questions at the intersection of AI, biotechnology, and biological security. 


Join the Chemical Weapons Convention Coalition and Arms Control Association for a virtual briefing, “Syria’s Chemical Weapons Legacy: Current Issues and Challenges,” on September 16 at 11:00 AM-12:30 PM ET. The event will examine Syria’s ongoing efforts to address the chemical weapons legacy of the Assad regime.



The Elephant in the Room: Biodefense Goes Localor Outbreaks Go Viral

By Carmen Shaw, Pandora Report Managing Editor

Figure 1. Fresh produce on display at a supermarket.
Source: Pexels.

Washington has long approached biodefense through a centralized, top-down approach, with federal agencies setting national priorities and strategies. However, recent outbreaks expose a critical vulnerability in that model: national biodefense is only as resilient as the local systems that carry it out. During this year’s cyclospora outbreak, Michigan investigators waited 12 days for Taco Bell supply chain records that a delayed FDA traceability rule would have required within 24 hours – a delay compounded by staffing shortages and an estimated $5.8 billion cut to CDC grant funding since last year. Meanwhile, Michigan was tracking more than 12,000 cyclospora cases while the national count stood at just 145.

The answer is not to abandon federal leadership, but to strengthen frontline capacity at the state and local levels. On Sep. 1, ASPR and NETEC announced a second round of STAND Awards, adding 21 hospitals across 16 states and territories to the National Special Pathogen System (NSPS), bringing the network to 75 facilities. In Bethel, Alaska, the Yukon-Kuskokwim Health Corporation has demonstrated how a tribal health system can build its own wastewater surveillance capacity, detecting influenza A up to 10 days before clinical data confirmed it and identifying rising COVID-19 and RSV activity. Uganda offers another example: during the 2026 Bundibugyo virus outbreak, the country met all three WHO 7-1-7 outbreak response benchmarks, detecting the outbreak in six days, notifying authorities in under one day, and completing early response actions within two days.

True biodefense preparedness requires federal leadership to actively strengthen state, local, tribal, and regional capacity, ensuring people and institutions are ready to detect and respond where threats first emerge.

Further Reading:


H5N1 Arrives on U.S. Mink Farms

By Margeaux Malone, Pandora Report Associate Editor 

The USDA confirmed avian influenza H5N1 on a Utah mink farm in mid-August, marking the virus’s first detection in a U.S. mink operation. Scientists have long flagged farmed mink as a potential pandemic risk as the size and density of the farms create a perfect environment in which the virus can mutate. An H5N1 outbreak in Spain in 2022 infected tens of thousands of minks and demonstrated the first documented evidence of mammal-to-mammal spread. Minks also have very similar respiratory systems to humans, creating conditions that researchers warn could help the virus evolve toward person-to-person transmission. Unfortunately, the concern isn’t purely theoretical. During the Covid-19 pandemic, mutated coronavirus strains circulated on fur farms across several European countries, and Denmark reported a dozen farm workers infected with a mink-linked variant that was less responsive to vaccines.

In addition to ethical and economic reasons, the zoonotic disease risk from farmed mink has already prompted most European countries to shut down or phase out fur farming. The U.S., however, has no federal ban on mink farming, and states including Utah, Wisconsin, and Minnesota still operate dozens of farms housing up to 12,000 animals apiece. Roughly 1.3 million pelts a year are produced in the U.S. for export, largely to Chinese fashion manufacturers. In response to the Utah detection, animal welfare groups are now pressing the USDA to phase out mink farming entirely, citing both the animal welfare concerns of the industry and its potential role as a breeding ground for the next pandemic virus.

Screwworm Zones Lifted in Texas

On a more encouraging note, USDA APHIS announced the release of two New World screwworm (NWS)-infested zones in Texas after coordinated surveillance, sterile fly releases, and livestock movement restrictions met federal criteria. It’s the first such release since the re-emergence of NWS in Texas in early June. The move lifts NWS-related movement requirements for producers in those zones, though other infested areas remain under restriction as the state-federal response continues. No new cattle infestations were detected in August in the U.S., but that does not mean NWS is disappearing just yet. Texas confirmed four new cases in domestic species in August: two in sheep, one in goats, and, most recently, in a dog detected on Monday, August 31st. Three of these cases remain active as of this week.

Further Reading: 


Schar School Professor Examines AI and Biological Weapons Risks

Dr. Sonia Ben Ouagrham-Gormley, Associate Professor of the Biodefense Graduate Program at George Mason University’s Schar School of Policy and Government, examines the “de-skilling” narrative surrounding AI and biological weapons policy in a new article for the Georgetown Journal of International Affairs. She argues that assessments of AI-driven biological threats often overestimate the ability of AI and other emerging technologies to lower barriers to biological weapons development while underestimating the importance of tacit knowledge, integration across stages of development, and the challenges of constructing durable sociotechnical systems. Ouagrham-Gormley calls for more empirically grounded threat assessments that consider the full bioweapons development process and inform targeted policy responses.


IN OTHER NEWS

Biosafety, Biosecurity, and Biotechnology

Public Health, CDC and Health Security

Emerging Infectious Diseases and Outbreaks

NEW: Bloomsday 2026

From Biotic: “Bloomsday 2026 will bring together researchers, ethicists, and policymakers to explore the emerging field of synthetic-cell engineering and the foundations needed to make the technology safe, reliable, and broadly accessible. The program will examine genome construction, computational tools, safety and security, dual-use risks, governance, and the ethical implications of engineered cellular systems.”

The event will take place on Thursday, September 10, 9:15 AM – 6:00 PM ET at the Science History Institute in Philadelphia. Learn more and register here.

NEW: Bioeconomy Summit

The Bioeconomy Summit, hosted by TechConnect, will bring together industry leaders, investors, federal officials, and experts to examine how the United States can strengthen and scale its bioeconomy. The summit will focus on aligning capital, policy, infrastructure, procurement, and industrial capacity; addressing vulnerabilities in biomanufacturing supply chains; and accelerating the deployment of bioindustrial technologies.

The summit will take place on Monday-Tuesday, September 21-22, at the National Harbor in Maryland. Learn more and register here.

NEW: Science of Evaluation of Artificial Intelligence for Life Sciences and Biotechnology Conference

From the National Academies: “This meeting brings together researchers and practitioners across various fields to define the emerging scientific method for artificial intelligence, focusing on benchmarks, leaderboards, challenges, and the evidence needed to trust systems that reason, act, discover, and operate in high-stakes domains, including the life sciences and biotechnology sectors.”

This conference will take place on Tuesday-Wednesday, September 22-23. Learn more and register here.

NEW: The Second Bio-Responsibility Policy Lecture: “From Lab Safety to Bio-Responsibility: Building the Human Infrastructure for Safe and Secure Science.”

From organizers: “Advances in the life sciences are creating new opportunities for health, biotechnology, and economic development while also presenting increasingly complex biosafety and biosecurity challenges. The lecture will examine how institutions can develop practical, risk-based biorisk management systems, with a focus on the trained professionals and institutional capacity needed to translate policy into practice. It will also explore approaches to expanding biorisk management capacity through scalable training, competency development, and institutional support, including in resource-constrained settings.”

The virtual lecture will take place on Thursday, September 24, 8:00 AM – 9:15 AM ET. Learn more and register here.

NEW: Frontiers in Synthetic Biology: SpudCells, Mirror Life and Societal Implications

From the Consortium on Law and Values: “Advances in cell engineering and synthetic biology offer enormous potential benefits, while raising ethical and policy issues. SpudCell, the first synthetic cell that can grow and reproduce, built from non-living chemicals, was developed by a team at the University of Minnesota. Scientists have cautioned against creating organisms with molecules that are mirror images of the biological components of known life, as existing organisms would have no immune defenses. Join three experts on synthetic biology, biosecurity, and bioethics to explore how to realize the promise of synthetic biology while controlling potential risks.”

This webinar will take place on Thursday, October 29, 3:00 PM ET. Learn more and register here.

Presidential Advisory Council on Combating Antibiotic-Resistant Bacteria (PACCARB)

From the Office of the Assistant Secretary for Health (OASH): “The 28th PACCARB public meeting will explore how microbiome science can support AMR prevention, drive novel interventions, and build public awareness and understanding of microbiome-focused health measures. The meeting will focus on innovative and emerging topics in antimicrobial resistance (AMR) and the microbiome.”

This hybrid meeting will take place on September 9-10 from 9:00 AM–5:00 PM ET. Learn more and register here.

Exponential AI and Biotech Growth: Translating Technical to Policy – Workshop

From AI for SynBio: “The continued acceleration of agentic artificial intelligence (AI), Biological Design Tools (BDTs), and Biological AI Models (BAIMs) has transformed the technological landscape, enabling tremendous benefits and potential misuse that could massively impact national security, defense, health, and economy. Mitigating this risk will require collaboration across Government, Industry, and Academia with both technical and policy focuses. Significant effort, especially at the federal level, has been made to raise awareness of this challenge, yet additional discussion is necessary to keep pace with the ever-evolving speed of this global technology.’

This workshop will take place from September 15-17 at the Hopkins Bloomberg Center in Washington, DC. Learn more and register here.

Data and Situational Awareness for Medical and Public Health Preparedness and Response: A Workshop Series

From the National Academies: “The Forum on Medical and Public Health Preparedness for Disasters and Emergencies workshop series will explore how medical, public health, emergency management, and critical infrastructure data are collected, integrated, analyzed, and translated into real-time information to support timely, coordinated decision-making before, during, and after disasters and emergencies.”

This workshop series will take place on September 23. Learn more and register here.

International Bio-Responsibility Conference 2027

Organized under the Bio-Responsibility Initiative at the Centre for Society and Policy (CSP), the conference brings together people to advance dialogue, build partnerships, and promote safe, secure, and responsible life science research, development, and innovation. The conference will host experts, policymakers, and practitioners around the world to discuss emerging biological risks and ways to strengthen responsible governance.

The deadline to register is September 30. Learn more and register here.

Training Course on ‘Biotechnology Innovation and Biosecurity’

From the International Centre for Genetic Engineering and Biotechnology (ICGEB) and the Biological Weapons Convention Implementation Support Unit: “This training focuses on strengthening capacities in biosecurity, biosafety, and biological risk management in the context of rapid advances in biotechnology with an integrated, interdisciplinary approach to manage biothreats at the intersection of humans, animals, plants and the environment. It addresses the governance, technical, and operational dimensions of preventing, detecting, and responding to biological threats, while promoting responsible and peaceful scientific research and innovation in accordance with article X of the Biological Weapons Convention (BWC).”

This in-person event will be held from October 12-16 in New Delhi, India. Learn more and apply here.

Biomanufacturing for Defense & Security Summit

From Diversified Solutions Incorporated (DSI Groups): “This event will bring together senior thought leaders and stakeholders from across DoW, Military Research Labs, Federal Government, Commercial Industry, & Academia to discuss how each are advancing biomanufacturing to enhance national security objectives, produce critical materials for defense applications, and strengthen the overall U.S. bioindustrial manufacturing base. Biomanufacturing is crucial for U.S. national security because it enables domestic production of critical materials, medicines, and defense supplies, reducing reliance on foreign adversaries, which in turn creates resilient supply chains for the military and economy.”

This event will take place from October 27-28 at the National Harbor, MD. Learn more and register here.

Pandora Report 8.28.2026: Syria’s Chemical Weapons Legacy, Bird Flu, and AI-Biosecurity

Welcome to this week’s Pandora Report! This issue highlights Syria’s ongoing chemical weapons legacy; Biodefense alumna Saskia Popescu and her work in global health security; emerging infectious disease threats, including H5N1 in Australian mammals and New World screwworm in Mexico; and the evolving landscape of AI-enabled biology and biosafety regulations. 


Join the Chemical Weapons Convention Coalition and Arms Control Association for a virtual briefing, “Syria’s Chemical Weapons Legacy: Current Issues and Challenges,” on September 16 at 11:00 AM-12:30 PM ET. The event will examine Syria’s ongoing efforts to address the chemical weapons legacy of the Assad regime.

Schar School Highlights Biodefense Alumna Saskia Popescu

The Schar School of Policy and Government profiled Dr. Saskia Popescu, 2019 Biodefense PhD alumna and current adjunct professor, highlighting her work in global health security, biosecurity policy, and outbreak preparedness. Popescu currently serves as CEO of the Global Health Security Network (GHSN), an Australian-based NGO dedicated to the detection, prevention, and control of infectious disease threats, and recently led the 4th Global Health Security Conference in Kuala Lumpur, Malaysia, which brought together more than 1,300 participants from 88 countries around the world. She continues to research biosecurity and resilience while teaching in the Schar School’s Biodefense program. Read the full profile here.

Figure 1. Dr. Saskia Popescu, Biodefense PhD ’19, leads the Global Health Security Network (GHSN) while continuing to teach and conduct research in biosecurity. Photo provided.

Bird Flu Reaches Australian Mammals

By Margeaux Malone, Pandora Report Associate Editor 

Australia’s H5N1 avian influenza outbreak has hit a new milestone as mammalian cases have been confirmed. A long-nosed fur seal was found dead on South Australia’s coast last week, marking the nation’s first mammalian case. The animal had no visible injuries and did not appear to be associated with other sick or dead marine mammals. Seals are especially vulnerable to avian influenza because they share coastal habitat closely with wild birds. Only days later, a red fox in suburban Adelaide became the first suspected case in a terrestrial mammal, likely infected after scavenging a sick bird. University of Sydney veterinary public health expert Michael Ward warned foxes could serve as a “bridge species,” potentially carrying the virus far inland to livestock like sheep. Australia’s red fox population is estimated at 1.7 million animals across 80% of the continent. More than 300 infection events have now been confirmed nationwide since the virus arrived in June, including deaths among ravens, penguins, terns, and gulls. Authorities are urging residents to leash dogs and keep cats indoors, while conservation sites like Cleland Wildlife Park begin vaccinating native birds. Fortunately, the virus has not reached Australia’s commercial poultry industry.

U.S.-Mexico Cattle Trade Resumes Despite Screwworm Concerns

The U.S. reopened its border to Mexican cattle this week, ending a year-long ban imposed due to concern for the spread of New World screwworm. Nearly 700 cattle crossed into Douglas, Arizona, on Monday, following a rigorous inspection procedure which includes RFID tagging and screening by specially trained screwworm-sniffing dogs. USDA chief veterinary officer Alan Huddleston called it a proof-of-concept protocol that could expand to more border crossings if successful. The reopening came just days after Sonora, the exporting state, reported its first screwworm case, though officials maintain the cattle pose no risk. Import volumes will scale gradually from 700 to 1,300 cattle daily. The ban previously pushed U.S. beef prices to record highs while forcing Mexican ranchers to sell domestically at steep discounts. Mexico currently has nearly 2,000 active screwworm cases nationwide, less than half of the infections reported a year ago, which authorities say shows progress in containing the outbreak.

Further Reading: 

Biodefense PhD Alum Chris Quillen Signs Book Deal

Dr. Chris Quillen, Biodefense PhD ’25, has signed a book contract with Routledge Taylor & Francis Group and its Contemporary Terrorism Series to publish his dissertation as The Critical Role of Scientists in Chemical and Biological Terrorism. His thesis argues that scientific personnel are the driving force behind terrorist efforts to develop chemical and biological weapons (CBW) rather than the leaders of terrorist groups. Although terrorist leaders may provide strategic vision, scientists often propose the idea of CBW programs to advance their own position within their groups. Once such programs begin, scientists—not leaders—select which CBW agents to pursue based on what they believe they can achieve, decide how best to pursue them based on what they know, and ultimately determine whether the effort succeeds or fails. Leaders play only a small part in these decisions. As a result, our current focus on targeting terrorist leaders is mistaken. Instead, efforts to prevent terrorist acquisition of CBW need to focus first and foremost on targeting the scientific personnel. Rather than treating scientists as non-combatant support personnel, these individuals should be targeted as active combatants like bombmakers and attack planners. The book will be available in 2027.

IN OTHER NEWS

Pandora Preparedness and Global Health Security

AI, Biotechnology, and Biosecurity

Presidential Advisory Council on Combating Antibiotic-Resistant Bacteria (PACCARB)

From the Office of the Assistant Secretary for Health (OASH): “The 28th PACCARB public meeting will explore how microbiome science can support AMR prevention, drive novel interventions, and build public awareness and understanding of microbiome-focused health measures. The meeting will focus on innovative and emerging topics in antimicrobial resistance (AMR) and the microbiome.”

This hybrid meeting will take place on September 9-10 from 9:00 AM–5:00 PM ET. Learn more and register here.

Exponential AI and Biotech Growth: Translating Technical to Policy – Workshop

From AI for SynBio: “The continued acceleration of agentic artificial intelligence (AI), Biological Design Tools (BDTs), and Biological AI Models (BAIMs) has transformed the technological landscape, enabling tremendous benefits and potential misuse that could massively impact national security, defense, health, and economy. Mitigating this risk will require collaboration across Government, Industry, and Academia with both technical and policy focuses. Significant effort, especially at the federal level, has been made to raise awareness of this challenge, yet additional discussion is necessary to keep pace with the ever-evolving speed of this global technology.’

This workshop will take place from September 15-17 at the Hopkins Bloomberg Center in Washington, DC. Learn more and register here.

Data and Situational Awareness for Medical and Public Health Preparedness and Response: A Workshop Series

From the National Academies: “The Forum on Medical and Public Health Preparedness for Disasters and Emergencies workshop series will explore how medical, public health, emergency management, and critical infrastructure data are collected, integrated, analyzed, and translated into real-time information to support timely, coordinated decision-making before, during, and after disasters and emergencies.”

This workshop series will take place on September 23. Learn more and register here.

International Bio-Responsibility Conference 2027

Organized under the Bio-Responsibility Initiative at the Centre for Society and Policy (CSP), the conference brings together people to advance dialogue, build partnerships, and promote safe, secure, and responsible life science research, development, and innovation. The conference will host experts, policymakers, and practitioners around the world to discuss emerging biological risks and ways to strengthen responsible governance.

The deadline to register is September 30. Learn more and register here.

Training Course on ‘Biotechnology Innovation and Biosecurity’

From the International Centre for Genetic Engineering and Biotechnology (ICGEB) and the Biological Weapons Convention Implementation Support Unit: “This training focuses on strengthening capacities in biosecurity, biosafety, and biological risk management in the context of rapid advances in biotechnology with an integrated, interdisciplinary approach to manage biothreats at the intersection of humans, animals, plants and the environment. It addresses the governance, technical, and operational dimensions of preventing, detecting, and responding to biological threats, while promoting responsible and peaceful scientific research and innovation in accordance with article X of the Biological Weapons Convention (BWC).”

This in-person event will be held from October 12-16 in New Delhi, India. Learn more and apply here.

Biomanufacturing for Defense & Security Summit

From Diversified Solutions Incorporated (DSI Groups): “This event will bring together senior thought leaders and stakeholders from across DoW, Military Research Labs, Federal Government, Commercial Industry, & Academia to discuss how each are advancing biomanufacturing to enhance national security objectives, produce critical materials for defense applications, and strengthen the overall U.S. bioindustrial manufacturing base. Biomanufacturing is crucial for U.S. national security because it enables domestic production of critical materials, medicines, and defense supplies, reducing reliance on foreign adversaries, which in turn creates resilient supply chains for the military and economy.”

This event will take place from October 27-28 at the National Harbor, MD. Learn more and register here.

Horizon Fellowship

From Horizon Institute for Public Service: “Through our fellowship, we place fully-funded fellows at host organizations to help tackle policy challenges related to artificial intelligence, biotechnology, and other emerging technologies. Fellows selected for our program receive policy-focused training, mentorship, and support in matching with a host organization for a full-time, fully-funded fellowship based in the Washington, DC area. Fellows join a collaborative, close-knit community of public service-oriented experts. Potential host organizations include executive branch offices, congressional offices, national laboratories, and think tanks.”

Learn more and submit your application here by August 30.

Asia Centre for Health Security (ACHS) Fellowship Programme

From ACHS: “The ACHS Fellowship Programme aims to inspire and connect the next generation of health security leaders and innovators. Launched in 2025 by ACHS, based at the Saw Swee Hock School of Public Health (SSHSPH), National University of Singapore (NUS), the ACHS Fellowship Programme is a highly competitive, part-time fellowship that provides graduate students and early- to mid-career professionals with an opportunity to deepen their expertise, expand their professional network, and build leadership skills through educational opportunities and project work.”

Learn more and submit your application here by August 31.

Pandora Report 8.24.2026: G20 Youth Diplomacy, H5N5, and Africa’s Health Security Index

Welcome to this week’s Pandora Report! This issue highlights reflections on the 2026 G20 Youth (Y20) Summit culminating in the G20 Youth Communiqué, emerging infectious disease threats including H5N5 and human screwworm infections, lessons from the Nuclear Threat Initiative’s Africa Health Security Index on strengthening health capacity and resilience, and the evolving landscape of biosafety, biosecurity, and AI-enabled biology.


Reflections on the 2026 G20 Youth (Y20) Summit: Realities, Global Consensus, and the Future of Diplomacy

By Carmen Shaw, U.S. Head Delegate for Food Security and Global Health (Y20 2026) | Biodefense PhD Student and Managing Editor, The Pandora Report

Figure 1. Over 100 global delegates convened in Washington, D.C., from August 11–14 for the 2026 G20 Youth (Y20) Summit. Delegates negotiated across five key tracks—global economy, energy, digital transformation, food security and global health, and conflict resolution—culminating in the 2026 G20 Youth Communiqué presented to G20 heads of state.

Over a week ago, more than 100 global delegates came together for the 2026 G20 Youth (Y20) Summit in Washington, DC. As the U.S. Head Delegate for Food Security and Global Health, participating in this summit on American soil during a period of profound political and economic transformation was both an honor and the responsibility of a lifetime. Hosted by Globally and the Young Professionals in Foreign Policy (YPFP), the summit culminated in months of rigorous multilateral negotiations among delegates, resulting in the publication of the 2026 G20 Youth Communiqué, which was formally presented to G20 leaders.

Figure 2. Delegates participate in multilateral negotiation sessions on policy proposals for the 2026 G20 Youth Communiqué report.

Containing 81 actionable policy recommendations, this communiqué offers a clear snapshot of global youth priorities across the global economy, digital innovation, energy, conflict and violence, food security, and global health. We did not shy away from hard or uncomfortable conversations; we engaged in them openly. Across these tracks, we debated frameworks for ethical AI governance, examined concrete pathways for securing energy supply chains, and pushed for Universal Health Coverage while prioritizing resilient healthcare financing. We also tackled deeply polarizing geopolitical issues, openly debating whether tariffs and economic sanctions can—and should—be used as tools of coercion in international affairs, while considering the legal protections required for displaced populations.

Throughout these negotiations, my objective was to ensure that high-level policy remained grounded in the realities facing communities and institutions. International frameworks have limited impact unless they protect and invest in the people who drive and depend on these global systems–farmers, workers, researchers, engineers, entrepreneurs, journalists, frontline healthcare professionals, humanitarian workers, and communities affected by conflict and displacement. Our experience demonstrated that effective multilateralism is built not on the absence of disagreement, but on deep empathy, strategic cooperation, and the willingness to find common ground.

There is no shortage of noise today about how divided our world has become, and America’s shifting role within it. Yet when you sit down at the negotiating table with young leaders from across the globe—doing the hours-long, painstaking work of reaching consensus across deep ideological divides—a very different story emerges. The future of international diplomacy and policy is stronger when young, empathetic, and pragmatic leaders step forward, listen openly, and work together to address the world’s most pressing challenges.

The channel between youth and our leaders is open. Our voices are unified, and the work of translating these policy recommendations into meaningful diplomatic action begins now.

Transmission Risk of Human H5N5

By Margeaux Malone, Pandora Report Associate Editor 

In a study published last week in the Journal of Virology, researchers evaluated the transmission risk of highly pathogenic avian influenza virus (HPAI) A(H5N5) following the world’s first confirmed human infection and fatality in November 2025. The patient, an older adult in Washington State with underlying health conditions, developed fever, confusion and worsening respiratory illness that required hospitalization and ultimately resulted in death. The patient kept a mixed backyard poultry flock, and environmental samples from the property tested positive for the H5N5 virus. No person-to-person spread was identified.

Testing the virus stain in human bronchial epithelial cells and in a ferret model, researchers found that the isolate replicated efficiently at human airway temperatures and caused fatal systemic disease but showed no capacity for airborne spread. Limited transmission occurred only with direct contact. Collectively, the results underscored the heterogeneity among clade 2.3.4.4b HPAI H5Nx viruses and the need for genotype-by-genotype evaluation of newly emerged influenza viruses to understand the public health risk.

The potential public health risk of HPAI is also at the forefront of the ongoing outbreak in Australian wildlife. Dr. Frank Wong, a Senior Research Scientist with the Australian Centre for Disease Preparedness (ACDP) said the risk of bird flu spreading to humans within the country remains very low. He noted an “ecological perfect storm” would be required for the virus to spill over, though that does not mitigate the need to stay on high alert. Clinicians should still inquire about recent contact with potentially infected animals and should strongly encourage seasonal influenza vaccination, particularly as national flu vaccine coverage has fallen from 45.6% in June 2020 to 26.2% in June 2026.

Human Screwworm Infections Climb in Mexico

More than 500 people in Mexico have been infected with New World screwworm (NWS), a sharp rise in infections from last year. A recent study in CDC’s Emerging Infectious Diseases examined 202 confirmed Mexican cases from April 2025 to March 2026 and found that reporting rose from roughly three cases a week in 2025 to more than nine a week in 2026. Legs or feet were affected in 55% of cases, with others involving the nose, mouth and eyes. Six patients died, though only one death was directly attributed to the infestation.

Although Mexico was declared free of NWS in 2003, this recent rise in human cases is not unexpected given the northward spread of the parasite, which re-emerged in animals in Mexico in 2024. The same obligate parasite affects livestock, wildlife, companion animals, and humans, so a rise in animal cases indicates local circulation of the fly and an increased risk for concurrent human infestation. Thus, NWS is both a public health and animal health problem and calls for a One Health approach. Since the spread of NWS is expected to continue for the foreseeable future, the authors urge surveillance, diagnostic preparedness, animal movement controls, and fly-suppression activities to be implemented proactively at the leading edge of expansion, rather than only after human cases are detected. Coordination between human health, animal health, wildlife, and agricultural sectors will be essential to guide prevention and control measures.

Further Reading: 

Exploring Global Health Security Policy: My Summer Internship Experience with the Nuclear Threat Initiative (NTI)

By Alex Kyabarongo, MS Biodefense Student, George Mason University

Figure 3. Alex Kyabarongo is a second-year MS Biodefense student at George Mason University, with a special interest in global health security policy and biothreat reduction programs. He recently completed a summer internship with NTI, where he contributed to the Africa Health Security Index.

As the Bundibugyo virus disease (BVD) outbreak in the Democratic Republic of Congo (DRC) outpaces containment efforts, with over 4,600 cases and more than 2,100 confirmed deaths as of August 12, the world remains more vulnerable to infectious disease threats than ever before. This outbreak—which experts say might be the deadliest Ebola outbreak yet due to its rapid spread—should serve as a stark reminder of the need to strengthen global health security programs. It should be a call to focus on improving disease surveillance capacities, biosafety and biosecurity, and other prevention, preparedness, and response efforts across the globe. Yet, this outbreak has occurred at a time when global health security financing remains fragmented, with shifts in international development assistance severely affecting health security programs in many countries, while the World Health Organization (WHO) Member States continue to face challenges in operationalizing the Pandemic Agreement.

It is such concerning global health security challenges that inspired me to enroll in the Master of Biodefense program at the Schar School of Policy and Government at George Mason University, with the intention of deepening my knowledge and understanding at the intersection of health and security. With the same aspirations, this summer, I joined the Nuclear Threat Initiative’s Global Biological Policy and Programs (NTI | bio) team for a 10-week internship. This internship came at an important point in my graduate school journey, as I remain with only one semester left before graduation. It was an important time to put my classroom experience into practice, and many topics explored during the previous semesters helped me transition smoothly to working in this important field during the internship period.

With the NTI | bio team, I gained hands-on experience working on projects focused on countering health security threats and emerging technology risks. It was such a unique opportunity to learn from the NTI | bio team and contribute to ongoing projects such as AIxBio and DNA synthesis screening. Importantly, it was great timing that I joined when the team was working on the Africa Health Security Index (AHS Index). The AHS Index, which was jointly developed by the Nuclear Threat Initiative, the Brown University Pandemic Centre, and the Science for Africa Foundation, builds upon the previous Global Health Security Index framework to assess African countries’ health security capacities. Working on this project after having taken Dr. Scott Wollek’s BIOD 710: Health Security Preparedness class during the spring semester was highly relevant and enabled me to put the class theoretical principles learned from class into practice. For the AHS Index, I specifically worked on the risk environment category, exploring why its regional scores have continuously declined over the last three Index issues and the implications of this trend for the implementation of Africa’s health security capacities.

The AHS Index scores show that Africa’s health security capacities have improved by 9.1 points from 2021, with strong improvements in disease surveillance, prevention, and response capacities. The region has expanded laboratory capacities but still struggles with biosafety and biosecurity systems, which increases the risks of laboratory accidents and the potential misuse of biological materials. Similarly, dual-use research oversight and the culture of responsible science remain critically low, at 1.9 out of 100 across the region, which ultimately serves as an alarming call for regional health security leaders to strengthen Dual-Use Research of Concern (DURC) governance. Most importantly, the region’s political and security risks, infrastructure inadequacies, and environmental risks remain areas of vulnerability. For more on the Index launch, explore my recently published blog article, and to explore the details of the Index data, results and the recommendations, visit the Index website.

Internship programs are an important aspect of students’ professional development. I am glad that the Schar School of Policy and Government has such a supportive career development team that continuously supported me throughout my internship period. I even got academic credit for the internship! The internship was very enriching, and I gained invaluable practical experience, which ultimately complements and enhances my current graduate program experience and prepares me for new challenges. I benefited from the excellent mentorship and support of the NTI | bio team, who provided me with an opportunity to explore the topics they were working on, guided me, and provided important feedback.

One important lesson I gained was the importance of collaboration and teamwork, which were central components of the AHS Index project. I deepened my understanding of health security policy, the research needed to identify gaps to be addressed, the importance of partnerships, and how these elements come together to address global health security challenges. The current Ebola crisis in Central Africa serves as a significant reference point of how important it is to invest in health security preparedness, improve capacity, and, most importantly, make health security an integral component of national security. It is internship programs like this that build the next generation of global health security leaders.

Further Reading:

NIH Releases a Draft Biosafety Policy for Research Involving Biohazards for Public Comment

The NIH has released a Draft Biosafety Policy for Research Involving Biohazards (Biosafety Policy) for public comment as part of its effort to strengthen and modernize biosafety oversight. In September 2025, NIH announced plans to strengthen and modernize biosafety oversight and has since engaged stakeholders to inform the development of an oversight framework that addresses risk. NIH invites stakeholders to provide feedback on the Draft Biosafety Policy and associated templates via its online portal, with comments accepted until October 19, 2026.

IN OTHER NEWS

Vaccines, Immunization Policy, and U.S. Public Health

Ebola and Other Infectious Disease Emergencies

AI, Bioweapons, and Emerging Biological Threats

Biosecurity, Resilience, and Defense Strategy

NEW: International Bio-Responsibility Conference 2027

Organized under the Bio-Responsibility Initiative at the Centre for Society and Policy (CSP), the conference brings together people to advance dialogue, build partnerships, and promote safe, secure, and responsible life science research, development, and innovation. The conference will host experts, policymakers, and practitioners around the world to discuss emerging biological risks and ways to strengthen responsible governance.

The deadline to register is September 30. Learn more and register here.

Presidential Advisory Council on Combating Antibiotic-Resistant Bacteria (PACCARB)

From the Office of the Assistant Secretary for Health (OASH): “The 28th PACCARB public meeting will explore how microbiome science can support AMR prevention, drive novel interventions, and build public awareness and understanding of microbiome-focused health measures. The meeting will focus on innovative and emerging topics in antimicrobial resistance (AMR) and the microbiome.”

This hybrid meeting will take place on September 9-10 from 9:00 AM–5:00 PM ET. Learn more and register here.

Exponential AI and Biotech Growth: Translating Technical to Policy – Workshop

From AI for SynBio: “The continued acceleration of agentic artificial intelligence (AI), Biological Design Tools (BDTs), and Biological AI Models (BAIMs) has transformed the technological landscape, enabling tremendous benefits and potential misuse that could massively impact national security, defense, health, and economy. Mitigating this risk will require collaboration across Government, Industry, and Academia with both technical and policy focuses. Significant effort, especially at the federal level, has been made to raise awareness of this challenge, yet additional discussion is necessary to keep pace with the ever-evolving speed of this global technology.’

This workshop will take place from September 15-17 at the Hopkins Bloomberg Center in Washington, DC. Learn more and register here.

Biosecurity Simulation Exercise (BSX 2026): Laboratory Incidents & Deliberate Biothreats

From the Asia Centre for Health Security: “This table-top simulation exercise aims to enhance inter-sectoral and inter-disciplinary preparedness for laboratory biosafety and biosecurity (LBB) and deliberate biothreat events (DBE). Through lectures, discussions, and structured, scenario-driven exercises, participants will explore decision-making to detect, risk-assess, and manage high-consequence biological incidents under conditions of incomplete information and unfolding events. Participants will collaborate in teams, building on expert perspectives to address issues in surveillance, diagnostics, public health response, security assessment, and risk communication.”

This in-person event will take place from August 27-28. Learn more and register here.

Data and Situational Awareness for Medical and Public Health Preparedness and Response: A Workshop Series

From the National Academies: “The Forum on Medical and Public Health Preparedness for Disasters and Emergencies workshop series will explore how medical, public health, emergency management, and critical infrastructure data are collected, integrated, analyzed, and translated into real-time information to support timely, coordinated decision-making before, during, and after disasters and emergencies.”

This workshop series will take place on September 23. Learn more and register here.

Training Course on ‘Biotechnology Innovation and Biosecurity’

From the International Centre for Genetic Engineering and Biotechnology (ICGEB) and the Biological Weapons Convention Implementation Support Unit: “This training focuses on strengthening capacities in biosecurity, biosafety, and biological risk management in the context of rapid advances in biotechnology with an integrated, interdisciplinary approach to manage biothreats at the intersection of humans, animals, plants and the environment. It addresses the governance, technical, and operational dimensions of preventing, detecting, and responding to biological threats, while promoting responsible and peaceful scientific research and innovation in accordance with article X of the Biological Weapons Convention (BWC).”

This in-person event will be held from October 12-16 in New Delhi, India. Learn more and apply here.

Biomanufacturing for Defense & Security Summit

From Diversified Solutions Incorporated (DSI Groups): “This event will bring together senior thought leaders and stakeholders from across DoW, Military Research Labs, Federal Government, Commercial Industry, & Academia to discuss how each are advancing biomanufacturing to enhance national security objectives, produce critical materials for defense applications, and strengthen the overall U.S. bioindustrial manufacturing base. Biomanufacturing is crucial for U.S. national security because it enables domestic production of critical materials, medicines, and defense supplies, reducing reliance on foreign adversaries, which in turn creates resilient supply chains for the military and economy.”

This event will take place from October 27-28 at the National Harbor, MD. Learn more and register here.

Researcher, Built Environment Team – Job Opening

From Blueprint Biosecurity: “The built environment encompasses the indoor spaces where people work, learn, gather, and receive care. Equipping these spaces with additional layers of protection against infectious airborne pathogens can help reduce risk in these spaces and support safer, more resilient communities. This work will focus on identifying and advancing promising interventions to mitigate pathogen transmission in occupied indoor spaces and strengthen society’s ability to contain outbreaks before they become widespread. Blueprint Biosecurity is hiring up to two Researchers to work directly with the Built Environment Program Director to lay the groundwork for new areas of interest and expand Blueprint’s portfolio.”

Learn more and submit your application here by August 21.

Respiratory Protection Program Officer, PPE Team – Job Opening

From Blueprint Biosecurity: “One of the most impactful ways to suppress pathogen transmission and save lives in a future outbreak is to ensure that highly protective respiratory PPE can be deployed to millions of critical workers on day one. Despite this, if a pandemic occurred tomorrow, U.S. stockpiles and supply chains would be unable to meet the demand. This problem motivated the development of the Blueprint for Pandemic PPE and has shaped our efforts to mobilize tens of millions of dollars toward advancing its goals. To build upon this momentum, Blueprint Biosecurity is hiring up to two Program Officers to expand our PPE team. These program officer roles are structured into two distinct tracks: Research Management or Grant Evaluation. Both positions will work closely with the PPE Program Director to help build a more resilient future in which critical workers have access to respirators during emergencies.

Learn more and submit your application here by August 21.

Horizon Fellowship

From Horizon Institute for Public Service: “Through our fellowship, we place fully-funded fellows at host organizations to help tackle policy challenges related to artificial intelligence, biotechnology, and other emerging technologies. Fellows selected for our program receive policy-focused training, mentorship, and support in matching with a host organization for a full-time, fully-funded fellowship based in the Washington, DC area. Fellows join a collaborative, close-knit community of public service-oriented experts. Potential host organizations include executive branch offices, congressional offices, national laboratories, and think tanks.”

Learn more and submit your application here by August 30.

Asia Centre for Health Security (ACHS) Fellowship Programme

From ACHS: “The ACHS Fellowship Programme aims to inspire and connect the next generation of health security leaders and innovators. Launched in 2025 by ACHS, based at the Saw Swee Hock School of Public Health (SSHSPH), National University of Singapore (NUS), the ACHS Fellowship Programme is a highly competitive, part-time fellowship that provides graduate students and early- to mid-career professionals with an opportunity to deepen their expertise, expand their professional network, and build leadership skills through educational opportunities and project work.”

Learn more and submit your application here by August 31.

WHO Internship Programme

From WHO: “A competent and dynamic health workforce at the heart of each health system is essential to advance global health goals. Countries need a pool of health professionals trained and exposed to the systems and processes in the health sector and who understand how stakeholders interact within the international health arena. WHO’s Internship Programme offers a wide range of opportunities for students and recent graduates to gain insight into the technical and administrative programmes of WHO and enrich their knowledge and experience in various areas, thereby contributing to the advancement of public health.”

Learn more and apply here.

OpenAI Bio Bug Bounty Program

From OpenAI: “As part of our ongoing efforts to strengthen our safeguards for advanced AI capabilities in biology, we’re evolving our GPT‑5.5 Bio Bug Bounty to become an ongoing private program—the OpenAI Bio Bounty Program. The program will remain focused on universal jailbreaks that can defeat our predefined biosafety challenge against OpenAI’s frontier models, starting with GPT‑5.6 and going forward. The reward for a universal jailbreak for the OpenAI Bio Bounty Program has been raised from $25,000 to $50,000 for both GPT‑5.6 and GPT‑5.5. Smaller awards may be granted for partial wins at our discretion.”

Learn more and submit your application here.

Disarmament and non-proliferation of WMD – Training Program

From Asser Institute and OPCW: “By 2026, pressure on the international arms control system has reached a point few experts anticipated would arrive so quickly, driven largely by intense geopolitical fragmentation. There is a critical need for professionals who possess the legal, technical, and diplomatic expertise to navigate these modern complexities. This intensive five-day training provides a comprehensive, practical overview of the international non-proliferation and disarmament framework.”

This program will take place from October 26-30 in The Hague, the Netherlands. Learn more and register here.

Pandora Report 8.7.2026: Fauci Contempt Vote, AIxBio Threats, and One Health Fronts

Welcome to this week’s Pandora Report! This issue highlights continued congressional scrutiny of Anthony Fauci following his Senate hearing, ongoing One Health threats from H5N1 avian influenza and New World screwworm, and efforts to address the opportunities and risks of AI-enabled biology. The Pandora Report will be taking a break next week and will return on August 21, 2026.

Thank you for reading, and we look forward to sharing more updates with you soon!


Join the National Academy of Medicine (NAM), the National Academies of Sciences, Engineering, and Medicine (NASEM), and the Coalition for Epidemic Preparedness Innovations (CEPI) for a two-day workshop, “Preparing for a Future of AI-Enabled Biology,” on August 11-12. The event will explore emerging technology, key uncertainties, and priorities for strengthening global preparedness.

Fauci Faces Continued Congressional Scrutiny Over COVID-19 Response

Following last week’s Senate hearing, former NIAID Director Dr. Anthony Fauci is facing continued congressional scrutiny over his role in the U.S. COVID-19 response. A Senate committee voted to hold Fauci in contempt of Congress after he declined to answer questions about his handling of the COVID-19 pandemic, citing his Fifth Amendment right against self-incrimination. The vote escalated a months-long dispute between Fauci and congressional investigators over questions related to COVID-19 origins, federal research funding, and pandemic decision-making. The proceedings followed the release of Fauci’s private COVID-era diary entries and additional records, including a copy of his government-issued phone. While critics have argued the materials raise concerns about transparency, fact-checkers have noted that they provide insight into Fauci’s personal experiences and frustrations during the crisis, but do not resolve ongoing scientific questions or debates surrounding COVID-19 origins.

Further Reading:

One Health on Two Fronts

By Margeaux Malone, Pandora Report Associate Editor 

Australia confirmed its first mass wildlife mortality from H5N1 bird flu earlier this week after more than 80 dead and sick greater crested terns were found on an island off South Australia’s south-east coast. Seventy-four cases have been confirmed nationally since June, mostly in South Australia, but fortunately no farms have yet been affected. In response to the recent mainland wildlife detections, the Australian government performed a risk assessment to better understand the potential impact on the country’s many species of native birds and mammals. More than 2,000 birds and mammals were listed from low to high risk based on their vulnerability and susceptibility, considering their habitat, ecology, behavior, and information from the global outbreaks.

Although the country’s biosecurity response has been excellent, Invasive Species Council CEO Jack Gough noted that funding to protect wildlife has gone backwards: “We won’t be able to stop bird flu spreading through wildlife, so the best response to that needs to be dealing with all the other threats. The foxes, the cats, the rats on islands, making sure wetlands are well connected, that we’re not seeing habitat destruction occurring in key nesting areas; that work hasn’t been happening at a scale which reflects the seriousness of this list.” Five seabirds, including the critically endangered Herald petrel, face extreme risk, meaning likely extinction if the virus reaches them, and more than 80 threatened species rank high or worse. Tasmanian devils, eastern quolls and several marine mammals would probably survive infection but with severely reduced populations. Vaccination requires two doses, which is impractical, if not impossible, in wild flocks, so trials are focused on captive breeding facilities.

Half a world away, Texas and surrounding states continue to battle New World screwworm. In an article published this week in Nature Ecology & Evolution, authors Andrews, Weese and Bogoch argue that the June 2026 screwworm re-emergence in Texas, the first overland US detection since the early 1980s, is the result of waning investment rather than any failure of the science. Sterile fly production and surveillance lapsed during the COVID-19 pandemic, and a front pushed south over 47 years rebounded to the Texas border within only three. They acknowledge that this is a One Health problem, in which human and animal health are linked. Human myiasis is a real though comparatively uncommon problem; a huge economic toll is borne from livestock and companion animal infestations, and wildlife carry the biggest burden in sheer morbidity and mortality. The elimination of screwworms from the U.S. will require long-term, active effort to keep at bay, meaning infrastructure that must be funded, staffed, and defended indefinitely. Anything short of this sustained investment will only lead to continual re-emergence and subsequent animal and financial losses.

Prevention is invisible when it works. A sterile fly plant running at capacity and a seabird colony free of rats produce no headlines, which is precisely why the funding behind them erodes quietly. The gaps go unnoticed until they explode open, and by then the cost of response will be orders of magnitude higher than the sustained maintenance would have been.

Further Reading: 

IN OTHER NEWS

U.S. Public Health Leadership, Preparedness, and Trust

Global Health Security, Pandemic Preparedness, and International Cooperation

Biological Threats, Outbreaks, and One Health

Emerging Technologies and Evolving WMD Risks

Biological War: A Scenario

From investigative journalist Annie Jacobsen, this book explores the catastrophic consequences of a deliberate biological attack or laboratory accident, tracing how a rapidly spreading pathogen could trigger cascading failures across public health systems, government, critical infrastructure, and society.

Drawing on interviews with senior experts in national security, medicine, science, and the military, Jacobsen presents a fast-paced, scenario-based narrative that examines the hours, days, and weeks following the release of a biological agent. Like her bestselling Nuclear War: A Scenario, the book uses a fictionalized but research-informed account to highlight the challenges of biodefense, pandemic preparedness, and crisis response in the face of an existential biological threat.

Further Reading:

NEW: Army Mad Scientist Series with Dr. James Giordano – Lecture

From the Institute for National Strategic Studies (INSS): “Join us for our virtual event, Braking Biowarfare: Deterrence Left-of-Denial featuring Dr. James Giordano, Head of the Center for Strategic Deterrence and Weapons of Mass Destruction Studies in the Institute for National Strategic Studies at the National Defense University. He will examine the need to shift contemporary biodefense beyond traditional reactive paradigms toward proactive strategies that prevent, delay, disrupt, and disincentivize the development and operationalization of weaponizable bioscience and biotechnology before their deployment.”

This virtual event will take place on Tuesday, August 18 from 12:00 PM-1:00 PM ET. Learn more and register here.

NEW: Presidential Advisory Council on Combating Antibiotic-Resistant Bacteria (PACCARB)

From the Office of the Assistant Secretary for Health (OASH): “The 28th PACCARB public meeting will explore how microbiome science can support AMR prevention, drive novel interventions, and build public awareness and understanding of microbiome-focused health measures. The meeting will focus on innovative and emerging topics in antimicrobial resistance (AMR) and the microbiome.”

This hybrid meeting will take place on September 9-10 from 9:00 AM–5:00 PM ET. Learn more and register here.

NEW: Exponential AI and Biotech Growth: Translating Technical to Policy – Workshop

From AI for SynBio: “The continued acceleration of agentic artificial intelligence (AI), Biological Design Tools (BDTs), and Biological AI Models (BAIMs) has transformed the technological landscape, enabling tremendous benefits and potential misuse that could massively impact national security, defense, health, and economy. Mitigating this risk will require collaboration across Government, Industry, and Academia with both technical and policy focuses. Significant effort, especially at the federal level, has been made to raise awareness of this challenge, yet additional discussion is necessary to keep pace with the ever-evolving speed of this global technology.’

This workshop will take place from September 15-17 at the Hopkins Bloomberg Center in Washington, DC. Learn more and register here.

Biosecurity Simulation Exercise (BSX 2026): Laboratory Incidents & Deliberate Biothreats

From the Asia Centre for Health Security: “This table-top simulation exercise aims to enhance inter-sectoral and inter-disciplinary preparedness for laboratory biosafety and biosecurity (LBB) and deliberate biothreat events (DBE). Through lectures, discussions, and structured, scenario-driven exercises, participants will explore decision-making to detect, risk-assess, and manage high-consequence biological incidents under conditions of incomplete information and unfolding events. Participants will collaborate in teams, building on expert perspectives to address issues in surveillance, diagnostics, public health response, security assessment, and risk communication.”

This in-person event will take place from August 27-28. Learn more and register here.

Data and Situational Awareness for Medical and Public Health Preparedness and Response: A Workshop Series

From the National Academies: “The Forum on Medical and Public Health Preparedness for Disasters and Emergencies workshop series will explore how medical, public health, emergency management, and critical infrastructure data are collected, integrated, analyzed, and translated into real-time information to support timely, coordinated decision-making before, during, and after disasters and emergencies.”

This workshop series will take place on September 23. Learn more and register here.

Training Course on ‘Biotechnology Innovation and Biosecurity’

From the International Centre for Genetic Engineering and Biotechnology (ICGEB) and the Biological Weapons Convention Implementation Support Unit: “This training focuses on strengthening capacities in biosecurity, biosafety, and biological risk management in the context of rapid advances in biotechnology with an integrated, interdisciplinary approach to manage biothreats at the intersection of humans, animals, plants and the environment. It addresses the governance, technical, and operational dimensions of preventing, detecting, and responding to biological threats, while promoting responsible and peaceful scientific research and innovation in accordance with article X of the Biological Weapons Convention (BWC).”

This in-person event will be held from October 12-16 in New Delhi, India. Learn more and apply here.

Biomanufacturing for Defense & Security Summit

From Diversified Solutions Incorporated (DSI Groups): “This event will bring together senior thought leaders and stakeholders from across DoW, Military Research Labs, Federal Government, Commercial Industry, & Academia to discuss how each are advancing biomanufacturing to enhance national security objectives, produce critical materials for defense applications, and strengthen the overall U.S. bioindustrial manufacturing base. Biomanufacturing is crucial for U.S. national security because it enables domestic production of critical materials, medicines, and defense supplies, reducing reliance on foreign adversaries, which in turn creates resilient supply chains for the military and economy.”

This event will take place from October 27-28 at the National Harbor, MD. Learn more and register here.

NEW: Researcher, Built Environment Team – Job Opening

From Blueprint Biosecurity: “The built environment encompasses the indoor spaces where people work, learn, gather, and receive care. Equipping these spaces with additional layers of protection against infectious airborne pathogens can help reduce risk in these spaces and support safer, more resilient communities. This work will focus on identifying and advancing promising interventions to mitigate pathogen transmission in occupied indoor spaces and strengthen society’s ability to contain outbreaks before they become widespread. Blueprint Biosecurity is hiring up to two Researchers to work directly with the Built Environment Program Director to lay the groundwork for new areas of interest and expand Blueprint’s portfolio.”

Learn more and submit your application here by August 21.

NEW: Respiratory Protection Program Officer, PPE Team – Job Opening

From Blueprint Biosecurity: “One of the most impactful ways to suppress pathogen transmission and save lives in a future outbreak is to ensure that highly protective respiratory PPE can be deployed to millions of critical workers on day one. Despite this, if a pandemic occurred tomorrow, U.S. stockpiles and supply chains would be unable to meet the demand. This problem motivated the development of the Blueprint for Pandemic PPE and has shaped our efforts to mobilize tens of millions of dollars toward advancing its goals. To build upon this momentum, Blueprint Biosecurity is hiring up to two Program Officers to expand our PPE team. These program officer roles are structured into two distinct tracks: Research Management or Grant Evaluation. Both positions will work closely with the PPE Program Director to help build a more resilient future in which critical workers have access to respirators during emergencies.

Learn more and submit your application here by August 21.

NEW: Horizon Fellowship

From Horizon Institute for Public Service: “Through our fellowship, we place fully-funded fellows at host organizations to help tackle policy challenges related to artificial intelligence, biotechnology, and other emerging technologies. Fellows selected for our program receive policy-focused training, mentorship, and support in matching with a host organization for a full-time, fully-funded fellowship based in the Washington, DC area. Fellows join a collaborative, close-knit community of public service-oriented experts. Potential host organizations include executive branch offices, congressional offices, national laboratories, and think tanks.”

Learn more and submit your application here by August 30.

NEW: Asia Centre for Health Security (ACHS) Fellowship Programme

From ACHS: “The ACHS Fellowship Programme aims to inspire and connect the next generation of health security leaders and innovators. Launched in 2025 by ACHS, based at the Saw Swee Hock School of Public Health (SSHSPH), National University of Singapore (NUS), the ACHS Fellowship Programme is a highly competitive, part-time fellowship that provides graduate students and early- to mid-career professionals with an opportunity to deepen their expertise, expand their professional network, and build leadership skills through educational opportunities and project work.”

Learn more and submit your application here by August 31.

WHO Internship Programme

From WHO: “A competent and dynamic health workforce at the heart of each health system is essential to advance global health goals. Countries need a pool of health professionals trained and exposed to the systems and processes in the health sector and who understand how stakeholders interact within the international health arena. WHO’s Internship Programme offers a wide range of opportunities for students and recent graduates to gain insight into the technical and administrative programmes of WHO and enrich their knowledge and experience in various areas, thereby contributing to the advancement of public health.”

Learn more and apply here.

OpenAI Bio Bug Bounty Program

From OpenAI: “As part of our ongoing efforts to strengthen our safeguards for advanced AI capabilities in biology, we’re evolving our GPT‑5.5 Bio Bug Bounty to become an ongoing private program—the OpenAI Bio Bounty Program. The program will remain focused on universal jailbreaks that can defeat our predefined biosafety challenge against OpenAI’s frontier models, starting with GPT‑5.6 and going forward. The reward for a universal jailbreak for the OpenAI Bio Bounty Program has been raised from $25,000 to $50,000 for both GPT‑5.6 and GPT‑5.5. Smaller awards may be granted for partial wins at our discretion.”

Learn more and submit your application here.

Disarmament and non-proliferation of WMD – Training Program

From Asser Institute and OPCW: “By 2026, pressure on the international arms control system has reached a point few experts anticipated would arrive so quickly, driven largely by intense geopolitical fragmentation. There is a critical need for professionals who possess the legal, technical, and diplomatic expertise to navigate these modern complexities. This intensive five-day training provides a comprehensive, practical overview of the international non-proliferation and disarmament framework.”

This program will take place from October 26-30 in The Hague, the Netherlands. Learn more and register here.

Pandora Report 7.31.2026: Is the U.S. Ready for the Next Pandemic?

Welcome to this week’s Pandora Report! This issue highlights Anthony Fauci’s contentious Senate hearing on the nation’s COVID-19 response, the state of U.S. public health preparedness as infectious disease threats continue to rise, ongoing H5N1 and New World screwworm challenges, and evolving biosecurity policies at home and abroad.


Anthony Fauci Pleads the Fifth During Contentious Senate COVID-19 Hearing

Former top US health official Anthony Fauci invoked his Fifth Amendment right against self-incrimination during a tense July 29 hearing before the Senate Committee on Homeland Security, declining to answer questions related to the origins of COVID-19 and the nation’s handling of the pandemic. The hearing, led by Committee Chairman Sen. Rand Paul (R-KY), followed the public release of Fauci’s COVID-era diaries and focused on allegations that federal funding supported risky viral research at the Wuhan Institute of Virology. Fauci’s attorneys advised him not to testify, citing ongoing legal concerns despite the presidential pardon he received from former President Joe Biden. Republican senators criticized his refusal to answer questions and raised the possibility of contempt proceedings, while Democratic lawmakers characterized the hearing as politically motivated and defended Fauci’s public health record.

Is America Becoming Less Prepared for the Next Pandemic?

By Carmen Shaw, Pandora Report Managing Editor

The United States is confronting several infectious disease threats at once – hantavirus, screwworm, Ebola, cyclospora, measles, whooping cough, and bird flu. Former CDC officials warn that major changes made by the administration to the nation’s public health infrastructure – reducing funding, cutting staff, changing priorities, and shuttering USAID – have left the US in worse shape than before the COVID-19 pandemic. According to The Guardian, 80% of senior leadership positions at the CDC still lack permanent officials, and the agency has lost an estimated 25-30% of its workforce. Given the dearth of proper “boots on the ground” experience, the US appears less prepared for the next major public health emergency.

It has also been reported that the Trump administration has quietly reduced the role of the HHS’ Agency for Healthcare Research and Quality (AHRQ), which supports research aimed at improving patient safety, healthcare quality, and emergency preparedness. Meanwhile, Politico reported that the State Department will move forward with dispensing approximately $600M in previously delayed vaccine funding after HHS Secretary Robert F. Kennedy Jr. held up the funding for months due to concerns about vaccine safety. Separately, a new analysis found that while the U.S. has strengthened several aspects of its Ebola response since the 2014-2016 West Africa epidemic – including airport screening, lab diagnostics, and hospital preparedness – experts warn that maintaining these capabilities will require sustained investment and experienced personnel.

These concerns surrounding the U.S. international disease response capacity grow as disease activity continues to rise nationwide. U.S. cyclospora infection cases have reached record levels in 2026 following multiple foodborne outbreaks. U.S. measles cases have surpassed last year’s total and reached their highest level in more than three decades, driven by declining childhood vaccination coverage and several outbreaks around the nation. Taken together, these developments paint a troubling picture for the US – even as disease threats continue to mount, the nation’s public health infrastructure appears to be backsliding.

California Judge Rules H5N1 Quarantine Locations to Stay Confidential

By Margeaux Malone, Pandora Report Associate Editor 

A Sacramento County Superior Court judge ruled against disclosing the names and locations of California dairies quarantined during the 2024-25 bird flu outbreak, siding with state agriculture officials. More than 750 dairies were quarantined statewide during that period as officials worked to contain the spread of highly pathogenic avian influenza. The suit was filed by the California Rural Legal Assistance (CRLA), which argued that making the information public would improve oversight of the state’s response, help protect dairy workers, and provide researchers with data to better understand the outbreak. The judge acknowledged the public interest in government transparency but concluded that protecting producer confidentiality would encourage farmers to report sick animals promptly and cooperate with disease investigations. Amanda Murray, California’s acting state veterinarian and branch chief of Animal Health and Food Safety Services, wrote, “Loss of this trust would likely have a chilling effect, wherein producers would either delay reporting or not report clinical signs of disease.” Out of fear of public backlash, some farms might have culled sick animals and disposed of them themselves, potentially spreading the disease unintentionally. Industry groups have praised the decision as vital to maintaining trust between producers and regulators, while CRLA says it’s weighing further legal options.

Cattle Imports from Mexico to Resume Amid Ongoing NWS Outbreaks

Last Friday, USDA announced a phased reopening of the US-Mexico border to cattle imports, despite the ongoing efforts to prevent further spread of New World Screwworm (NWS) into the country. Imports will start August 24 at the Douglas, Arizona port, with New Mexico crossings to follow pending Mexico’s compliance with a joint action plan targeting NWS. Sonora and Chihuahua were identified as lower-risk source states in Mexico due to stronger inspection infrastructure. The decision follows sustained pressure from Republicans and cattle industry groups to reopen the border amid elevated beef prices, a concern shared by the administration, which aims to lower prices ahead of the upcoming midterm elections.

Agriculture Secretary Brooke Rollins had previously resisted reopening the southern border over screwworm concerns, while acknowledging the economic challenges it posed to various sectors of the industry in Texas. The Biden administration first closed the border to cattle imports in late 2024 following detection of NWS in southern Mexico. The Trump administration then temporarily reopened the border from January to May 2025, before closing it again as screwworms moved northward in Mexico. While many industry groups applaud the move, others, including the United States Cattlemen’s Association (USCA), remain wary that reopening risks reintroducing the parasite before containment is complete. USCA President Justin Tupper responded to the decision, saying, “Any effort to lower beef prices must not come at the expense of U.S. cattle herd health. We’ve been encouraged to rebuild the domestic herd; it is of utmost importance, and unnecessary exposure to animal health threats is a risk we do not need to take.”

Further Reading: 

IN OTHER NEWS

Infectious Disease Outbreaks

Biosecurity Governance and High-Risk Research

Rising Temps, Rising Risks: Infectious Disease in the 2026 El Niño Year

From the Pandemic Center: “Climate variability, including El Niño-driven shifts in temperature and rainfall, is reshaping infectious disease risks by altering the environments where pathogens and vectors thrive. This year is progressing towards a historically severe El Niño event — a naturally occurring climate pattern characterized by the warming of surface waters in the central and eastern Pacific Ocean.

What impact will this compounding climate event have on disease prevalence, and which regions are most vulnerable? In this Pandemic Center webinar, we will convene an expert panel to discuss these questions and more.”

This webinar will take place on July 31 at 12:00 PM ET. Learn more and register here.

Data and Situational Awareness for Medical and Public Health Preparedness and Response: A Workshop Series

From the National Academies: “The Forum on Medical and Public Health Preparedness for Disasters and Emergencies workshop series will explore how medical, public health, emergency management, and critical infrastructure data are collected, integrated, analyzed, and translated into real-time information to support timely, coordinated decision-making before, during, and after disasters and emergencies.”

This workshop series will take place on September 23. Learn more and register here.

Preparing for a Future of AI-Enabled Biology – A Workshop

From the National Academy of Medicine (NAM): “Artificial intelligence (AI) is transforming the life sciences, including how researchers study biology, develop vaccines and treatments, and detect disease outbreaks. While these advances could improve public health and preparedness, they also raise important questions about safety, security, and the possibility of misuse.”

This event will take place on August 11-12. Learn more and register here.

Ninth Session of the Working Group on the Strengthening of the Biological Weapons Convention

From the United Nations Office for Disarmament Affairs (UNODA): “We will convene the Ninth Session of the Working Group on the Strengthening of the Biological Weapons Convention (BWC). Chaired by Ambassador Frederico S. Duque Estrada Meyer of Brazil, the meeting will bring together State Parties, international organizations, academic institutions, and civil society representatives to continue discussions on strengthening the Convention and advancing efforts to address biological threats. Public sessions will be webcast through UN Web TV, and side events are expected throughout the week.

This event will take place from August 17-21 at the Palais des Nations in Geneva, Switzerland. Learn more and register by July 31st here.

Biosecurity Simulation Exercise (BSX 2026): Laboratory Incidents & Deliberate Biothreats

From the Asia Centre for Health Security: “This table-top simulation exercise aims to enhance inter-sectoral and inter-disciplinary preparedness for laboratory biosafety and biosecurity (LBB) and deliberate biothreat events (DBE). Through lectures, discussions, and structured, scenario-driven exercises, participants will explore decision-making to detect, risk-assess, and manage high-consequence biological incidents under conditions of incomplete information and unfolding events. Participants will collaborate in teams, building on expert perspectives to address issues in surveillance, diagnostics, public health response, security assessment, and risk communication.”

This in-person event will take place from August 27-28. Learn more and register here.

Training Course on ‘Biotechnology Innovation and Biosecurity’

From the International Centre for Genetic Engineering and Biotechnology (ICGEB) and the Biological Weapons Convention Implementation Support Unit: “This training focuses on strengthening capacities in biosecurity, biosafety, and biological risk management in the context of rapid advances in biotechnology with an integrated, interdisciplinary approach to manage biothreats at the intersection of humans, animals, plants and the environment. It addresses the governance, technical, and operational dimensions of preventing, detecting, and responding to biological threats, while promoting responsible and peaceful scientific research and innovation in accordance with article X of the Biological Weapons Convention (BWC).”

This in-person event will be held from October 12-16 in New Delhi, India. Learn more and apply here.

Biomanufacturing for Defense & Security Summit

From Diversified Solutions Incorporated (DSI Groups): “This event will bring together senior thought leaders and stakeholders from across DoW, Military Research Labs, Federal Government, Commercial Industry, & Academia to discuss how each are advancing biomanufacturing to enhance national security objectives, produce critical materials for defense applications, and strengthen the overall U.S. bioindustrial manufacturing base. Biomanufacturing is crucial for U.S. national security because it enables domestic production of critical materials, medicines, and defense supplies, reducing reliance on foreign adversaries, which in turn creates resilient supply chains for the military and economy.”

This event will take place from October 27-28 at the National Harbor, MD. Learn more and register here.

WHO Internship Programme

From WHO: “A competent and dynamic health workforce at the heart of each health system is essential to advance global health goals. Countries need a pool of health professionals trained and exposed to the systems and processes in the health sector and who understand how stakeholders interact within the international health arena. WHO’s Internship Programme offers a wide range of opportunities for students and recent graduates to gain insight into the technical and administrative programmes of WHO and enrich their knowledge and experience in various areas, thereby contributing to the advancement of public health.”

Learn more and apply here.

OpenAI Bio Bug Bounty Program

From OpenAI: “As part of our ongoing efforts to strengthen our safeguards for advanced AI capabilities in biology, we’re evolving our GPT‑5.5 Bio Bug Bounty to become an ongoing private program—the OpenAI Bio Bounty Program. The program will remain focused on universal jailbreaks that can defeat our predefined biosafety challenge against OpenAI’s frontier models, starting with GPT‑5.6 and going forward. The reward for a universal jailbreak for the OpenAI Bio Bounty Program has been raised from $25,000 to $50,000 for both GPT‑5.6 and GPT‑5.5. Smaller awards may be granted for partial wins at our discretion.”

Learn more and submit your application here.

Disarmament and non-proliferation of WMD – Training Program

From Asser Institute and OPCW: “By 2026, pressure on the international arms control system has reached a point few experts anticipated would arrive so quickly, driven largely by intense geopolitical fragmentation. There is a critical need for professionals who possess the legal, technical, and diplomatic expertise to navigate these modern complexities. This intensive five-day training provides a comprehensive, practical overview of the international non-proliferation and disarmament framework.”

This program will take place from October 26-30 in The Hague, the Netherlands. Learn more and register here.

Pandora Report 7.24.2026

Welcome to this week’s Pandora Report! This issue highlights a multistate Cyclospora outbreak linked to recalled iceberg lettuce served at Taco Bell locations, updates on the continued global spread of H5N1 avian influenza from Cambodia to New Zealand, and the DHS’s new AI-enabled biological threat detection challenge under the Genesis Mission.


Taco Bell Cyclospora Outbreak Linked to Recalled Iceberg Lettuce

By Carmen Shaw, Pandora Report Managing Editor

The CDC, FDA, and public health officials are investigating a new multistate outbreak of the diarrhea-causing parasite Cyclospora, which has been linked to iceberg lettuce served at Taco Bell locations in 9 states. As of July 24, at least 1,947 confirmed illnesses and 98 hospitalizations have been reported across Illinois, Indiana, Kansas, Kentucky, Michigan, Ohio, Oklahoma, Pennsylvania, and West Virginia, with no deaths recorded. Epidemiological investigations have identified iceberg lettuce sourced from central Mexico by Taylor Farms de Mexico as the likely source of the outbreak, prompting a voluntary recall of all affected lettuce products distributed to consumers, restaurants, and retailers in at least 27 states.

Illness onset dates range from June 22 to July 20, 2026. Despite the recall, public health officials expect to see the number of confirmed cases continue to rise because it can take up to 6 weeks for laboratory testing to determine whether an illness is associated with the outbreak. The FDA continues to advise the public to avoid all products listed in Taylor Farms’ voluntary recall.

The outbreak has also temporarily affected Taco Bell’s business performance, with consumer foot traffic declining nearly 30% following public notification of the investigation. However, industry analysts expect the financial impact to be short-lived, citing the company’s rapid removal of affected lettuce from its supply chain and proactive public communications. The CDC also continues to investigate other unrelated cyclosporiasis outbreaks occurring nationwide.

Further Reading:

Bird Flu Claims New Territory from Cambodia to New Zealand

By Margeaux Malone, Pandora Report Associate Editor 

Cambodia has confirmed its fifth human H5N1 case of the year, involving a 9-month-old girl who is currently hospitalized and receiving intensive care. No source of infection has yet been identified, though her close contacts are being given Tamiflu as a precaution. Cambodia reported 19 human cases in 2025, eight of them fatal, with most recent infections involving a reassorted strain which blends an older clade circulating since 2014 with the globally spreading 2.3.4.4b clade. Meanwhile in the US, APHIS reported a second consecutive egg-farm outbreak in Utah, bringing the 30-day national poultry toll to 1.49 million. New cattle detections in Utah and Idaho added four cases each, pushing the year’s total to 81.

Just days after confirming bird flu in a migratory bird, New Zealand detected the first infection of H5N1 in a native bird late last week. The country’s chief veterinary officer Mary van Andel says the disease is likely to become endemic within months, mirroring outcomes elsewhere in the world. Further spillover into native wildlife is probable and experts warn the consequences could be severe. In response, the Department of Conservation has begun vaccinating 300 core breeding birds across five of the country’s most endangered species, including kākāpō and takahē. Officials stress there is no food safety risk, and chicken and eggs remain safe to eat.

These developments fit a broader global picture. The dominant strain of highly pathogenic avian influenza, H5N1 clade 2.3.4.4b, has now reached every continent following the recent detections in Australia and New Zealand, closing the last geographic gap in the outbreak. Since 2020, the virus has proven unusually adept at jumping into mammals, including foxes, seals, and, unexpectedly, U.S. dairy cattle. Fortunately, human infection remains uncommon, with over 880 sporadic cases reported to the World Health Organization (WHO) since 1997 and no sustained human-to-human transmission documented. Still, scientists are watching newer, more severe genotypes and evidence of possible asymptomatic infection, which points to a virus that continues to evolve and could eventually pose a global pandemic risk.

Further Reading: 

DHS Launches AI-Driven Biological Threat Detection Challenge

The U.S. Department of Homeland Security (DHS) Science & Technology Directorate (S&T) announced a new set of national challenges – part of the “Genesis Mission” – aimed at bolstering the U.S.’ security and global leadership in critical and emerging technology. This includes an initiative to deploy AI-enabled platforms to rapidly detect, characterize, and attribute emerging biological threats to safeguard public health and the bioeconomy. By leveraging federal biological data resources, national laboratories, and cross-agency collaboration, this effort aims to shorten detection and response timelines, deter adversaries, and protect Americans from the misuse of biotechnology.

IN OTHER NEWS 

NEW: DC Biosecurity Happy Hour

Join the DC Biosecurity Happy Hour, an informal event for biosecurity enthusiasts in DC to get to know each other outside of Zoom calls and talk about new ideas in the space.

This event will take place on Tuesday, July 28, from 6:30 PM-8:30 PM ET. Learn more and register here.

NEW: Rising Temps, Rising Risks: Infectious Disease in the 2026 El Niño Year

From the Pandemic Center: “Climate variability, including El Niño-driven shifts in temperature and rainfall, is reshaping infectious disease risks by altering the environments where pathogens and vectors thrive. This year is progressing towards a historically severe El Niño event — a naturally occurring climate pattern characterized by the warming of surface waters in the central and eastern Pacific Ocean.

What impact will this compounding climate event have on disease prevalence, and which regions are most vulnerable? In this Pandemic Center webinar, we will convene an expert panel to discuss these questions and more.”

This webinar will take place on July 31 at 12:00 PM ET. Learn more and register here.

Data and Situational Awareness for Medical and Public Health Preparedness and Response: A Workshop Series

From the National Academies: “The Forum on Medical and Public Health Preparedness for Disasters and Emergencies workshop series will explore how medical, public health, emergency management, and critical infrastructure data are collected, integrated, analyzed, and translated into real-time information to support timely, coordinated decision-making before, during, and after disasters and emergencies.”

This workshop series will take place on July 21, July 28, and September 23. Learn more and register here.

Tracking Health Security Progress and Building Resilience in Africa – A Webinar

From the Nuclear Threat Initiative (NTI): “The world is shifting from a period of urgent health actions to one of vast growing neglect, even as biological threats continue to rise. Against this backdrop, the 2026 Africa Health Security Index shows great progress has been made across the continent – but substantial gaps remain.

Join NTI, the Brown University Pandemic Center, Economist Enterprise, and the Science for Africa Foundation for a discussion of the findings and recommendations of the 2026 Africa Health Security (AHS) Index, an independent assessment of health security capacities in Africa.

This webinar will convene global experts and policymakers to discuss how the AHS Index can shape policy decision-making and drive meaningful action to strengthen health security capacities and improve preparedness for future epidemics and pandemics.”

This virtual event will take place on July 29 from 8:30 AM-10:00 AM ET (3:30-5:00 PM EAT). Learn more and register here.

Preparing for a Future of AI-Enabled Biology – A Workshop

From the National Academy of Medicine (NAM): “Artificial intelligence (AI) is transforming the life sciences, including how researchers study biology, develop vaccines and treatments, and detect disease outbreaks. While these advances could improve public health and preparedness, they also raise important questions about safety, security, and the possibility of misuse.”

This event will take place on August 11-12. Learn more and register here.

Ninth Session of the Working Group on the Strengthening of the Biological Weapons Convention

From the United Nations Office for Disarmament Affairs (UNODA): “We will convene the Ninth Session of the Working Group on the Strengthening of the Biological Weapons Convention (BWC). Chaired by Ambassador Frederico S. Duque Estrada Meyer of Brazil, the meeting will bring together State Parties, international organizations, academic institutions, and civil society representatives to continue discussions on strengthening the Convention and advancing efforts to address biological threats. Public sessions will be webcast through UN Web TV, and side events are expected throughout the week.

This event will take place from August 17-21 at the Palais des Nations in Geneva, Switzerland. Learn more and register by July 31st here.

Biosecurity Simulation Exercise (BSX 2026): Laboratory Incidents & Deliberate Biothreats

From the Asia Centre for Health Security: “This table-top simulation exercise aims to enhance inter-sectoral and inter-disciplinary preparedness for laboratory biosafety and biosecurity (LBB) and deliberate biothreat events (DBE). Through lectures, discussions, and structured, scenario-driven exercises, participants will explore decision-making to detect, risk-assess, and manage high-consequence biological incidents under conditions of incomplete information and unfolding events. Participants will collaborate in teams, building on expert perspectives to address issues in surveillance, diagnostics, public health response, security assessment, and risk communication.”

This in-person event will take place from August 27-28. Learn more and register here.

Training Course on ‘Biotechnology Innovation and Biosecurity’

From the International Centre for Genetic Engineering and Biotechnology (ICGEB) and the Biological Weapons Convention Implementation Support Unit: “This training focuses on strengthening capacities in biosecurity, biosafety, and biological risk management in the context of rapid advances in biotechnology with an integrated, interdisciplinary approach to manage biothreats at the intersection of humans, animals, plants and the environment. It addresses the governance, technical, and operational dimensions of preventing, detecting, and responding to biological threats, while promoting responsible and peaceful scientific research and innovation in accordance with article X of the Biological Weapons Convention (BWC).”

This in-person event will be held from October 12-16 in New Delhi, India. Learn more and apply here.

Biomanufacturing for Defense & Security Summit

From Diversified Solutions Incorporated (DSI Groups): “This event will bring together senior thought leaders and stakeholders from across DoW, Military Research Labs, Federal Government, Commercial Industry, & Academia to discuss how each are advancing biomanufacturing to enhance national security objectives, produce critical materials for defense applications, and strengthen the overall U.S. bioindustrial manufacturing base. Biomanufacturing is crucial for U.S. national security because it enables domestic production of critical materials, medicines, and defense supplies, reducing reliance on foreign adversaries, which in turn creates resilient supply chains for the military and economy.”

This event will take place from October 27-28 at the National Harbor, MD. Learn more and register here.

WHO Internship Programme

From WHO: “A competent and dynamic health workforce at the heart of each health system is essential to advance global health goals. Countries need a pool of health professionals trained and exposed to the systems and processes in the health sector and who understand how stakeholders interact within the international health arena. WHO’s Internship Programme offers a wide range of opportunities for students and recent graduates to gain insight into the technical and administrative programmes of WHO and enrich their knowledge and experience in various areas, thereby contributing to the advancement of public health.”

Learn more and apply here.

OpenAI Bio Bug Bounty Program

From OpenAI: “As part of our ongoing efforts to strengthen our safeguards for advanced AI capabilities in biology, we’re evolving our GPT‑5.5 Bio Bug Bounty to become an ongoing private program—the OpenAI Bio Bounty Program. The program will remain focused on universal jailbreaks that can defeat our predefined biosafety challenge against OpenAI’s frontier models, starting with GPT‑5.6 and going forward. The reward for a universal jailbreak for the OpenAI Bio Bounty Program has been raised from $25,000 to $50,000 for both GPT‑5.6 and GPT‑5.5. Smaller awards may be granted for partial wins at our discretion.”

Learn more and submit your application here.

Disarmament and non-proliferation of WMD – Training Program

From Asser Institute and OPCW: “By 2026, pressure on the international arms control system has reached a point few experts anticipated would arrive so quickly, driven largely by intense geopolitical fragmentation. There is a critical need for professionals who possess the legal, technical, and diplomatic expertise to navigate these modern complexities. This intensive five-day training provides a comprehensive, practical overview of the international non-proliferation and disarmament framework.”

This program will take place from October 26-30 in The Hague, the Netherlands. Learn more and register here.

Pandora Report 7.17.2026

Welcome to this week’s Pandora Report! This issue highlights a new proposal to modernize U.S. biosecurity governance, the continued global spread of H5N1 avian influenza and New World screwworm, the escalating Ebola outbreak in the DRC, and upcoming events and opportunities focused on biosecurity, One Health, pandemic preparedness, and emerging biotechnology.


FAS Proposes Overhaul of U.S. Biosecurity Governance Towards Adaptive Frameworks

A new briefing paper from the Federation of American Scientists (FAS), authored by Sam Weiss Evans, argues that the United States’ fragmented biosecurity governance system is ill-equipped to address emerging risks posed by biotechnology and calls for a fundamental shift from reactive, piecemeal oversight to a centralized, adaptive governance model. The paper contends that existing authorities are dispersed across multiple agencies, creating regulatory gaps as advances in areas such as AI-enabled biology, gene synthesis, and cloud laboratories outpace current policies. To modernize biosecurity, the author outlines seven design requirements for a new institutional framework, including proactive and multi-sectoral risk identification, oversight spanning the full innovation lifecycle, the ability to develop and test new governing tools, and continuous adaptation as technologies evolve.

Bird Flu and New World Screwworm: A Week in Review

By Margeaux Malone, Pandora Report Associate Editor 

H5N1 avian influenza has once again expanded into new territory. New Zealand confirmed its first case this week after a migratory seabird found near Wellington tested positive. Fortunately, officials have found no evidence of poultry infections, mass wildlife mortality, or transmission between wild birds within the country. Nevertheless, health officials have started a vaccination program for 300 core breeding birds from five endangered species, including the flightless takahe and kakapo. The vaccine was trialed last year with no adverse side effects, but it is uncertain how effective it was given that those birds had not been exposed to the virus. “We are ​incredibly worried about New Zealand’s biodiversity because our birds have never ​had to deal with anything like this before,” said Brett Gartrell, professor of wildlife health at Massey University.

Meanwhile, multiple human H5N1 bird flu cases were reported in Asia. Cambodia reported its 5th human H5N1 case of 2026, a 9-month-old girl from Phnom Penh confirmed positive on July 9. No source of exposure has been identified yet. This brings Cambodia’s total to 39 cases since a 2023 reemergence of the older 2.3.2.1e clade. Bangladesh confirmed its 3rd H5N1 case of the year in a child from Sylhet Division.

As New World screwworm continues to spread, officials warn that feral hogs could carry the parasite into Oklahoma. So far, Texas has not reported any screwworm cases in wildlife, though this may be due to the challenge of monitoring non-domestic animals. Feral swine pose a unique risk because they roam widely, are difficult to track, and often develop injuries from fighting that would attract infestations. Screwworm control in these animals would be extremely difficult as infested animals could not be medicated. Though the wild populations are a problem, state veterinarian Dr. Rod Hall said the most immediate threat is currently illegal interstate transport of hogs, a felony in Oklahoma. Officials are coordinating with hunters, wildlife rehabilitators, and commercial hunting operations to expand surveillance. Ranchers and the public are urged to report animals with unusual wounds or maggots immediately.

Further Reading: 

IN OTHER NEWS 

Foodborne Disease & Public Health

Ebola Outbreak Response

Global Health Policy and Governance

Emerging Biotechnology, AI, and Synthetic Biology

NEW: Strategic Preparedness Exchange and Archive Repository (SPEAR) and Practical Preparedness Solutions – A Webinar

From Shield Initiative: “The SHIELD Initiative invites you to a dynamic webinar introducing SPEAR, the Strategic Preparedness Exchange and Archive Repository. This new, user-friendly platform is designed to make preparedness and response resources accessible to frontline preparedness practitioners across public health, health care, and emergency management.”

This virtual event will take place on July 21 from 3:00–4:00 PM ET. Learn more and register here.

NEW: Bagels & Biotech: Synthetic Cells

Join the National Academy of Medicine and science, technology, and policy professionals from the Washington, DC region for breakfast and conversations as we explore how breakthroughs in synthetic cell systems could transform biomedical and health applications, including therapeutics, diagnostics, regenerative medicine, and distributed biomanufacturing.

This event will take place on July 22 from 8:30-10:30 AM ET at The Keck Center in Washington, DC. Learn more and register here.  

NEW: The Global One Health Movement: Why Social Scientists are Critical to Making One Health Thinking, Acting, and Decision-Making the Default for Humankind – a Webinar

From the One Health Commission: “As global health challenges become increasingly interconnected, the integration of social sciences into the One Health approach is more important than ever. In this inspiring session, Dr. Stroud will discuss how social scientists contribute to making One Health thinking, collaboration, and evidence-based decision-making the global standard. The webinar will also explore innovative approaches to addressing food safety, food security, public health, animal health, environmental sustainability, and other complex challenges through interdisciplinary collaboration.”

This virtual event will take place on July 22 at 11:00 AM ET (5:00 PM CET). Learn more and register here.

The 100 Days Mission and the Future of Vaccine Readiness – Webinar

From the Pandemic Center Biosecurity Game Changers Fellows: “Convened and moderated by and intended for early-to-mid-career professionals, the Game Changers Seminar Series shines a spotlight on major challenges that will confront the next generation of biosecurity leaders and explores impactful next steps that can be taken to lean forward faster to prevent biological crises.

This seminar will explore the future of vaccine readiness through the lens of the 100 Days Mission. The discussion will examine the scientific, policy, financing, and implementation requirements to achieving this goal, drawing on lessons from the recent Ebola and Hantavirus outbreaks to inform future pandemic preparedness.”

This webinar will take place on July 17 at 11:00 AM ET. Learn more and register here.

Data and Situational Awareness for Medical and Public Health Preparedness and Response: A Workshop Series

From the National Academies: “The Forum on Medical and Public Health Preparedness for Disasters and Emergencies workshop series will explore how medical, public health, emergency management, and critical infrastructure data are collected, integrated, analyzed, and translated into real-time information to support timely, coordinated decision-making before, during, and after disasters and emergencies.”

This workshop series will take place on July 21, July 28, and September 23. Learn more and register here.

Tracking Health Security Progress and Building Resilience in Africa – A Webinar

From the Nuclear Threat Initiative (NTI): “The world is shifting from a period of urgent health actions to one of vast growing neglect, even as biological threats continue to rise. Against this backdrop, the 2026 Africa Health Security Index shows great progress has been made across the continent – but substantial gaps remain.

Join NTI, the Brown University Pandemic Center, Economist Enterprise, and the Science for Africa Foundation for a discussion of the findings and recommendations of the 2026 Africa Health Security (AHS) Index, an independent assessment of health security capacities in Africa.

This webinar will convene global experts and policymakers to discuss how the AHS Index can shape policy decision-making and drive meaningful action to strengthen health security capacities and improve preparedness for future epidemics and pandemics.”

This virtual event will take place on July 29 from 8:30 AM-10:00 AM ET (3:30-5:00 PM EAT). Learn more and register here.

Preparing for a Future of AI-Enabled Biology – A Workshop

From the National Academy of Medicine (NAM): “Artificial intelligence (AI) is transforming the life sciences, including how researchers study biology, develop vaccines and treatments, and detect disease outbreaks. While these advances could improve public health and preparedness, they also raise important questions about safety, security, and the possibility of misuse.”

This event will take place on August 11-12. Learn more and register here.

Ninth Session of the Working Group on the Strengthening of the Biological Weapons Convention

From the United Nations Office for Disarmament Affairs (UNODA): “We will convene the Ninth Session of the Working Group on the Strengthening of the Biological Weapons Convention (BWC). Chaired by Ambassador Frederico S. Duque Estrada Meyer of Brazil, the meeting will bring together State Parties, international organizations, academic institutions, and civil society representatives to continue discussions on strengthening the Convention and advancing efforts to address biological threats. Public sessions will be webcast through UN Web TV, and side events are expected throughout the week.

This event will take place from August 17-21 at the Palais des Nations in Geneva, Switzerland. Learn more and register by July 31st here.

Biosecurity Simulation Exercise (BSX 2026): Laboratory Incidents & Deliberate Biothreats

From the Asia Centre for Health Security: “This table-top simulation exercise aims to enhance inter-sectoral and inter-disciplinary preparedness for laboratory biosafety and biosecurity (LBB) and deliberate biothreat events (DBE). Through lectures, discussions, and structured, scenario-driven exercises, participants will explore decision-making to detect, risk-assess, and manage high-consequence biological incidents under conditions of incomplete information and unfolding events. Participants will collaborate in teams, building on expert perspectives to address issues in surveillance, diagnostics, public health response, security assessment, and risk communication.”

This in-person event will take place from August 27-28. Learn more and register here.

Training Course on ‘Biotechnology Innovation and Biosecurity’

From the International Centre for Genetic Engineering and Biotechnology (ICGEB) and the Biological Weapons Convention Implementation Support Unit: “This training focuses on strengthening capacities in biosecurity, biosafety, and biological risk management in the context of rapid advances in biotechnology with an integrated, interdisciplinary approach to manage biothreats at the intersection of humans, animals, plants and the environment. It addresses the governance, technical, and operational dimensions of preventing, detecting, and responding to biological threats, while promoting responsible and peaceful scientific research and innovation in accordance with article X of the Biological Weapons Convention (BWC).”

This in-person event will be held from October 12-16 in New Delhi, India. Learn more and apply here.

Biomanufacturing for Defense & Security Summit

From Diversified Solutions Incorporated (DSI Groups): “This event will bring together senior thought leaders and stakeholders from across DoW, Military Research Labs, Federal Government, Commercial Industry, & Academia to discuss how each are advancing biomanufacturing to enhance national security objectives, produce critical materials for defense applications, and strengthen the overall U.S. bioindustrial manufacturing base. Biomanufacturing is crucial for U.S. national security because it enables domestic production of critical materials, medicines, and defense supplies, reducing reliance on foreign adversaries, which in turn creates resilient supply chains for the military and economy.”

This event will take place from October 27-28 at the National Harbor, MD. Learn more and register here.

NEW: WHO Internship Programme

From WHO: “A competent and dynamic health workforce at the heart of each health system is essential to advance global health goals. Countries need a pool of health professionals trained and exposed to the systems and processes in the health sector and who understand how stakeholders interact within the international health arena. WHO’s Internship Programme offers a wide range of opportunities for students and recent graduates to gain insight into the technical and administrative programmes of WHO and enrich their knowledge and experience in various areas, thereby contributing to the advancement of public health.”

Learn more and apply here.

NEW: OpenAI Bio Bug Bounty Program

From OpenAI: “As part of our ongoing efforts to strengthen our safeguards for advanced AI capabilities in biology, we’re evolving our GPT‑5.5 Bio Bug Bounty to become an ongoing private program—the OpenAI Bio Bounty Program. The program will remain focused on universal jailbreaks that can defeat our predefined biosafety challenge against OpenAI’s frontier models, starting with GPT‑5.6 and going forward. The reward for a universal jailbreak for the OpenAI Bio Bounty Program has been raised from $25,000 to $50,000 for both GPT‑5.6 and GPT‑5.5. Smaller awards may be granted for partial wins at our discretion.”

Learn more and submit your application here.

NEW: Disarmament and non-proliferation of WMD – Training Program

From Asser Institute and OPCW: “By 2026, pressure on the international arms control system has reached a point few experts anticipated would arrive so quickly, driven largely by intense geopolitical fragmentation. There is a critical need for professionals who possess the legal, technical, and diplomatic expertise to navigate these modern complexities. This intensive five-day training provides a comprehensive, practical overview of the international non-proliferation and disarmament framework.”

This program will take place from October 26-30 in The Hague, the Netherlands. Learn more and register here.

Senior Fellow and Director, The Technology and Global Security Program – Job Opening

From The Henry L. Stimson Center: “The Henry L. Stimson Center, an award-winning foreign policy think tank, seeks a highly motivated individual to serve as Senior Fellow and Director of its newly established Technology and Global Security Program. The Program will work on the security implications of a broad range of emerging and converging technologies, including quantum technologies, artificial intelligence, biotechnology, additive manufacturing, uncrewed systems, distributed ledger technologies, nuclear technologies, and other innovations reshaping the international security landscape.”

Learn more and submit your application here.

Pandora Report 7.10.2026

Welcome to this week’s Pandora Report! This issue highlights the upcoming One Health Day campaign, the latest global H5N1 developments and renewed calls to strengthen oversight of the U.S. wildlife trade, the launch of Global BioFutures, and new analyses of evolving terrorism and counterterrorism trends in 2026.

One Health Day 2026 🌍

The annual One Health Day campaign is approaching on November 3rd and serves as a global reminder that the health of humans, animals, plants, and the environment are deeply interconnected.

Bird Flu: Australia’s seabirds to America’s dairy herds

By Margeaux Malone, Pandora Report Associate Editor 

Highly pathogenic avian influenza (HPAI) H5N1 remains a global presence, but the current impact differs by region.

In Australia, New South Wales became the latest state to confirm a case of bird flu after a migratory giant petrel tested positive, bringing the country to six infections across three states. The news follows a milestone last month, when Australia became the final continent to record a mainland case. Officials continue to stress that there is no spread to commercial poultry, that egg and chicken supplies are unaffected, and that human infections remain rare.

North America, by contrast, is in a seasonal lull. The United States passed a full month with no HPAI in commercial poultry. Canada’s last case in a commercial flock was in mid-May, and according to a recent report, all outbreaks have been declared closed. U.S. dairy cattle have not been so fortunate. Idaho recorded 40 newly infected herds in June, the bulk of all new domestic bird flu detections. Idaho’s state veterinarian, Dr. Scott Leibsle, said the virus strain is spreading cow-to-cow rather than from wild birds, complicating containment. State officials are considering expanding surveillance efforts and additional countermeasures like vaccines, if one becomes available. “Biosecurity only goes so far when you have a dairy of several thousand cattle that are infected with the virus,” Leibsle said. Nationally, the tally now stands at 1,154 affected herds across 20 states since the outbreak began.

A Call to Rethink the U.S. Wildlife Trade

The recent reemergence of New World screwworm in the U.S. has drawn national attention to livestock disease threats, but some argue it should also call attention to a historically overlooked pandemic risk: the country’s largely unregulated wildlife trade.

In a recent piece in Think Global Health, author Neil M. Vora argues that while officials police livestock and people at the border, they continue to ignore the tens of millions of live wild animals imported each year, primarily for the exotic pet market. According to the piece, most pandemics since 1918 have stemmed from zoonotic pathogens, and mammals in the wildlife trade are far more likely to share pathogens with humans. Over the past two decades, nearly three billion animals representing more than 20,000 species were legally imported into the United States; however, legal importation doesn’t mean these animals are safe. Imported wildlife are rarely screened for diseases, and importers and exporters often only need to attest to their animals’ health. Cases like the mpox outbreak in the Midwest in 2003 linked to Ghanian rodents or a mass mortality event among sloths in Florida earlier this year from a novel gammaherpesvirus highlight the disease risks posed by importation of exotic species.

The author points to fragmented oversight as a core problem, noting that responsibility is scattered across state and federal agencies with no single body accountable. Rather than waiting for Congress to pass new legislation, he contends that federal officials already have broad power under Title 42 to prevent introduction and transmission of communicable disease from foreign countries and the CDC has clear authority to regulate importation of animals into the country to reduce and prevent the spread of disease. Vora ultimately calls for creation of a carefully selected “permitted list” for trade, consisting only of species deemed to have a low risk for harboring pathogens based on rigorous review of scientific evidence, with all others barred except in limited cases. Although some may argue this conclusion is too restrictive, the article raises worthwhile points to consider for pandemic preparedness against zoonotic disease.

Further Reading:  

The Launch of Global BioFutures

This week, Dr. Aparupa Sengupta announced the launch of Global BioFutures, a mission-driven organization building talent, institutions, and governance to strengthen global health security and shape responsible biotechnology. Dr. Sengupta has worked for more than a decade, most recently at the Nuclear Threat Initiative (NTI), at the intersection of biological innovation, emerging technologies, biosecurity, and global policy. Biotechnology and artificial intelligence (AI) are advancing at an unprecedented speed, but the governance, institutions, and talent needed to guide them responsibly are not keeping pace—particularly across the Global South. Yet this is where some of the world’s fastest-growing bioeconomies, scientific talent, and biotechnology innovation are emerging. Global BioFutures was founded to strengthen biological capacity by advancing AI-biotechnology governance, biosecurity, field building in the Global South, talent development, and strategic partnerships across emerging biotechnology ecosystems. Professor Gregory D. Koblentz, Director of the Biodefense Graduate Program at the Schar School of Policy and Government, has been selected to serve on the group’s founding Strategic Advisory Board. According to Professor Koblentz, “Global BioFutures recognizes that identifying emerging biorisks and devising innovative policies for mitigating these risks will require diverse perspectives from a broad range of stakeholders, especially in countries with booming bioeconomies. Global BioFuture’s awareness-raising and capacity-building initiatives reflect the reality that today’s biosecurity challenges are global—and so are the solutions”. 

GMU Professor Highlights Terrorism and Counterterrorism Trends in First Half of 2026

In two new analyses for Homeland Security Today, Dr. Mahmut Cengiz, adjunct professor at George Mason University’s Schar School of Policy and Government, examines how both terrorist organizations and counterterrorism efforts are evolving during the first half of 2026. Taken together, these articles identify key trends shaping global threat landscape, including the growing convergence of terrorism with transnational crime and emerging technologies, as well as the ways governments are adapting their operational strategies to address increasingly complex and interconnected security challenges.

IN OTHER NEWS 

Global Health Security & Emerging Infectious Diseases

Chemical Weapons, OPCW & International Security

Biotechnology Governance & Biosecurity

Intelligence, Oversight, and Emerging Threats

NEW: The 100 Days Mission and the Future of Vaccine Readiness – Webinar

From the Pandemic Center Biosecurity Game Changers Fellows: “Convened and moderated by and intended for early-to-mid-career professionals, the Game Changers Seminar Series shines a spotlight on major challenges that will confront the next generation of biosecurity leaders and explores impactful next steps that can be taken to lean forward faster to prevent biological crises.

This seminar will explore the future of vaccine readiness through the lens of the 100 Days Mission. The discussion will examine the scientific, policy, financing, and implementation requirements to achieving this goal, drawing on lessons from the recent Ebola and Hantavirus outbreaks to inform future pandemic preparedness.”

This webinar will take place on July 17 at 11:00 AM ET. Learn more and register here.

NEW: Biomanufacturing for Defense & Security Summit

From Diversified Solutions Incorporated (DSI Groups): “This event will bring together senior thought leaders and stakeholders from across DoW, Military Research Labs, Federal Government, Commercial Industry, & Academia to discuss how each are advancing biomanufacturing to enhance national security objectives, produce critical materials for defense applications, and strengthen the overall U.S. bioindustrial manufacturing base. Biomanufacturing is crucial for U.S. national security because it enables domestic production of critical materials, medicines, and defense supplies, reducing reliance on foreign adversaries, which in turn creates resilient supply chains for the military and economy.”

This event will take place from October 27-28 at the National Harbor, MD. Learn more and register here.

Data and Situational Awareness for Medical and Public Health Preparedness and Response: A Workshop Series 

From the National Academies: “The Forum on Medical and Public Health Preparedness for Disasters and Emergencies workshop series will explore how medical, public health, emergency management, and critical infrastructure data are collected, integrated, analyzed, and translated into real-time information to support timely, coordinated decision-making before, during, and after disasters and emergencies.” 

Sessions of the workshop series will take place on July 16, July 21, and July 28, followed by a capstone session on September 23. Learn more and register here

Tracking Health Security Progress and Building Resilience in Africa – A Webinar 

From the Nuclear Threat Initiative (NTI): “The world is shifting from a period of urgent health actions to one of vast growing neglect, even as biological threats continue to rise. Against this backdrop, the 2026 Africa Health Security Index shows great progress has been made across the continent – but substantial gaps remain. 

Join NTI, the Brown University Pandemic Center, Economist Enterprise, and the Science for Africa Foundation for a discussion of the findings and recommendations of the 2026 Africa Health Security (AHS) Index, an independent assessment of health security capacities in Africa. 

This webinar will convene global experts and policymakers to discuss how the AHS Index can shape policy decision-making and drive meaningful action to strengthen health security capacities and improve preparedness for future epidemics and pandemics.” 

This webinar will take place on July 29 from 3:30 – 5:00 PM EAT (8:30 AM – 10:00 AM ET). Learn more and register here

Preparing for a Future of AI-Enabled Biology 

From the National Academy of Medicine (NAM): “Artificial intelligence (AI) is transforming the life sciences, including how researchers study biology, develop vaccines and treatments, and detect disease outbreaks. While these advances could improve public health and preparedness, they also raise important questions about safety, security, and the possibility of misuse. 

To better understand these issues, the National Academy of Medicine, in collaboration with the National Academies of Sciences, Engineering, and Medicine and with support from the Coalition for Epidemic Preparedness Innovations (CEPI), will convene a two-day workshop on preparing for the future of AI-enabled biology. 

The workshop will bring together experts from public health, medicine, biotechnology, artificial intelligence, biosecurity, government, and industry to explore how AI-enabled biological risks may evolve over the next decade.” 

This hybrid event will take place on August 11-12, 2026. Learn more and register here.

Ninth Session of the Working Group on the Strengthening of the Biological Weapons Convention  

From the United Nations Office for Disarmament Affairs (UNODA): “We will convene the Ninth Session of the Working Group on the Strengthening of the Biological Weapons Convention (BWC). Chaired by Ambassador Frederico S. Duque Estrada Meyer of Brazil, the meeting will bring together State Parties, international organizations, academic institutions, and civil society representatives to continue discussions on strengthening the Convention and advancing efforts to address biological threats. Public sessions will be webcast through UN Web TV, and side events are expected throughout the week.  

This event will take place from August 17-21 at the Palais des Nations in Geneva, Switzerland. Learn more and register by July 31 here 

Biosecurity Simulation Exercise (BSX 2026): Laboratory Incidents & Deliberate Biothreats 

From the Asia Centre for Health Security: “This table-top simulation exercise aims to enhance inter-sectoral and inter-disciplinary preparedness for laboratory biosafety and biosecurity (LBB) and deliberate biothreat events (DBE). Through lectures, discussions, and structured, scenario-driven exercises, participants will explore decision-making to detect, risk-assess, and manage high-consequence biological incidents under conditions of incomplete information and unfolding events. Participants will collaborate in teams, building on expert perspectives to address issues in surveillance, diagnostics, public health response, security assessment, and risk communication.” 

This in-person event will be held from August 27-28. Learn more and register here

Training Course on ‘Biotechnology Innovation and Biosecurity’ 

From the International Centre for Genetic Engineering and Biotechnology (ICGEB) and the Biological Weapons Convention Implementation Support Unit: “This training focuses on strengthening capacities in biosecurity, biosafety, and biological risk management in the context of rapid advances in biotechnology with an integrated, interdisciplinary approach to manage biothreats at the intersection of humans, animals, plants and the environment. It addresses the governance, technical, and operational dimensions of preventing, detecting, and responding to biological threats, while promoting responsible and peaceful scientific research and innovation in accordance with article X of the Biological Weapons Convention (BWC).” 

This in-person event will be held from October 12 – 16 in New Delhi, India. Learn more and apply here

NEW: Senior Fellow and Director, The Technology and Global Security Program – Job Opening

From The Henry L. Stimson Center: “The Henry L. Stimson Center, an award-winning foreign policy think tank, seeks a highly motivated individual to serve as Senior Fellow and Director of its newly established Technology and Global Security Program. The Program will work on the security implications of a broad range of emerging and converging technologies, including quantum technologies, artificial intelligence, biotechnology, additive manufacturing, uncrewed systems, distributed ledger technologies, nuclear technologies, and other innovations reshaping the international security landscape.”

Learn more and submit your application here.

Pandora Report 12.13.2024

This week’s Pandora Report covers the rush to find the former Assad regime’s hidden chemical weapons, a recent study on H5N1’s potential to become an efficient human pathogen, Nobel laureates’ call for the Senate to block RFK Jr. from becoming HHS Secretary, and more.

Assad Regime Falls

On Sunday, Syrian rebels continued their advance, taking the capital city of Damascus and forcing the country’s long-time leader, President Bashar al-Assad, to flee to Moscow. This ended the country’s 13-year-long civil war and toppled a brutal dictatorship known to have, among other things, used chemical weapons against its own civilians. Now, the country is strapped for cash and being led by opposition forces with limited experience in governance.

Adding to the chaos is the mad dash to locate the former Assad regime’s chemical weapons it hid from inspectors. Among the list of missing weapons are more than 360 tons of mustard gas that the Assad regime admitted to making, but never fully accounted for. There are also five missing tons of precursors for sarin that the Assad regime claimed were “Lost during transportation, due to traffic accidents.”

The OPCW said it is monitoring the situation, reaffirming its commitment to “clarifying gaps, discrepancies, and inconsistencies in Syrian chemical weapons declaration amidst political transition.” Rebels in the south of the country have reached out to the OPCW for support in safely disposing of a cache of CW they found. One US official told the press the US is working with other countries in the Middle East to prevent these weapons from falling into the wrong hands. Meanwhile, Israel reported that it has destroyed CW and other weapons caches while seizing areas along its shared border with the country it claims are part of a demilitarized buffer zone.

Further Reading and Listening:

New Study Finds Single Mutation in Bovine Influenza H5N1 Hemagglutinin Switches Specificity to Human Receptors

A recent study in Science found that a single glutamine to leucine mutation in clade 2.3.4.4b-an H5N1 virus widespread in US dairy cattle that has caused a few mild human cases-at residue 226 of the virus hemagglutinin “was sufficient to enact the change from avian to human specificity.” This means that this virus that currently cannot infect humans very easily could be just one mutation away from being able to do so much more effectively. This finding alone does not mean that this mutation in nature would be guaranteed to make this virus an efficient human pathogen, but it might mean that this version of the virus has a higher zoonotic potential than other H5N1 viruses.

Further Reading:

Investigation Launched into Queensland Lab Incident

An investigation has been launched by Australian authorities into the “major breach” of biosafety protocols that occurred at a state-run laboratory in Queensland in 2021. It was revealed that 323 virus samples-nearly 100 of which were live samples of Hendra virus-were missing. According to Health Minister Tim Nicholls, the incident was only discovered in August of 2023, and the lab is unable to confirm whether the materials were removed or destroyed, though there is no suggestion that they were taken or stolen from the lab.

Top Wuhan Virologist Says WIV Holds No Close Relatives to SARS-CoV-2

Shi Zhengli, the virologist leading coronavirus research at the Wuhan Institute of Virology (WIV) when the COVID-19 pandemic began, presented data on dozens of new coronaviruses collected from bats in southern China at a conference in Japan last week. Shi has said repeatedly that SARS-CoV-2 was never seen nor studied in her lab, but some have continued to insist that one of the bat coronaviruses collected by her team was closely related to it. As a result, Shi promised to sequence the genomes of the viruses stored in her freezers and release the resulting data.

The analysis presented at the conference has not been peer reviewed and includes data from the whole genomes of 56 new betacoronaviruses in addition to some partial sequences. All of these viruses were collected between 2004 and 2021. Shi explained at the conference that none of the viruses she has sequenced are the most recent ancestors of SARS-CoV-2 and that “We didn’t find any new sequences which are more closely related to SARS-CoV-1 and SARS-CoV-2.”

The known viruses that are closest to SARS-CoV-2 were found in bats in Laos and southern China. However, years (or decades) have passed since these viruses split from their common ancestor with SARS-CoV-2. Shi has long since collaborated with EcoHealth Alliance, which previously received US federal funding that was suspended because of inadequate oversight of research activities at the WIV. This collaboration has produced a larger analysis of more than 230 sequences that EcoHealth Alliance’s Peter Daszak says will be submitted for peer review and publication in the coming weeks.

Further Reading: “PLA Looks into China-US Collaboration in Biosecurity Research,” Stephen Chen, SCMP

75+ Nobel Laureates Urge Senate Not to Confirm RFK Jr.

77 winners of the Nobel Prize in Medicine, Chemistry, Physics, and Economics have signed a letter (below) urging the Senate not to confirm President-Elect Trump’s pick to lead HHS-Robert F. Kennedy Jr.. This is a rare example of Nobel laureates coming together against a US Cabinet choice, according to Sir Richard Roberts, winner of the 1993 Nobel Prize in Medicine and a drafter of the letter. The letter criticizes Kennedy’s lack of experience in public health in addition to his widely criticized opinions on topics like drinking water fluoridation and vaccines for measles and polio. The letter reads in part, “In view of his record, placing Mr. Kennedy in charge of DHHS would put the public’s health in jeopardy and undermine America’s global leadership in the health sciences, in both the public and commercial sectors…We strongly urge you to vote against the confirmation of his appointment as Secretary of the DHHS.”

Further Reading:

“2024 ABSA Conference Summary”

Biodefense MS Student Lena Kropke discusses her experience at the 67th Annual Biosafety and Biosecurity Conference in this Pandora Report event summary, writing in part “Attending this conference not only reaffirmed that biosafety and biosecurity are vital components of international security, but also showcased the incredible dedication of professionals who work tirelessly toward this mission. Moreover, it offered an introduction to an amazing network of biosafety and security professionals.”

Read more about Lena’s time attending the conference in Phoenix here.

“Disincentivizing Bioweapons: Theory and Policy Approaches”

This NTI essay collection is “…designed to encourage the exploration and identification of potential solutions to disincentivize states from developing or using biological weapons,” and aims to “bridge theory and practical policy-relevant approaches to develop new approaches to invigorate international efforts to reduce biological threats.” Its fifth essay, “Two Competing Bioweapons Nonproliferation Policies: Deterrence by Denial and Discussion,” was authored by Sonia Ben Ouagrham-Gormley, Associate Professor at the Schar School.

Mitigating Arboviral Threat and Strengthening Public Health Preparedness: Proceedings of a Workshop

From NASEM: “Arboviruses, or viruses carried by arthropods like mosquitoes or ticks, are responsible for hundreds of thousands of deaths worldwide each year. As the climate changes globally, the geographic distribution of these diseases, including Zika, dengue, chikungunya, West Nile, and yellow fever, are steadily expanding. The National Academies Forum on Microbial Threats hosted a public workshop in December 2023 to explore avenues of threat reduction from known and emerging arboviral diseases in the context of public health preparedness and capacity building. The workshop featured talks from experts in entomology, public health, ecology, virology, immunology, disease modeling, and urban planning.”

Read this Proceedings of a Workshop for free here.

“The Current Pathogenicity and Potential Risk Assessment of Nipah Virus as Potential Cause of “Disease X”: A Narrative Review”

Mehnaz et al. recently published this article in Health Science Reports: “Background and Aims…The World Health Organization (WHO) recognized the potential for a severe international epidemic and introduced the term “Disease X” to classify pathogens that not yet identified. The Nipah virus (NiV) is highly dangerous due to its zoonotic nature, high mortality rate, and ability to cause severe clinical symptoms in humans. In this review, we gather the latest information on the NiV and its potential to become a significant candidate for Disease X.”

“Methods…We performed a thorough review of articles published in PubMed, Scopus, and Google Scholar using appropriate MeSH terms and keywords. Studies reported NiV infection were considered for this review.”

“Results…The NiV exhibits different epidemiological patterns in different countries that calls for customized prevention and control strategies. Genetic analysis highlights NiV’s ability to mutate that alters possible treatment options. Transmission typically involves bats as the primary reservoir, with humans becoming infected either through intermediate hosts or food. This shows NiV’s complex nature, including its ability to reach the central nervous system through the olfactory nerve. Promising treatment options, such as monoclonal antibodies, antivirals, and ongoing vaccine research, provide hope. However, the virus’s adaptability, human-to-human transmission, and the lack of specific antiviral therapy raise concerns about its potential to cause a global pandemic. The interconnection between animals, humans, and the environment stresses the need for a One Health approach to tackle emerging infectious disease by NiV.”

“Conclusion…Global collaboration, surveillance, and research investments are imperative for the preparation of future pandemics. The ongoing COVID-19 challenges underscoring the critical need for sustained scientific endeavors, global leadership, and recognition of the prominence of NiV as a candidate for the potential Disease X.”

“Engineering Biology Public Trust Survey Findings”

From the UK’s Department for Science, Innovation and Technology, these findings are the result of a survey on public perceptions of engineering biology in relation to five application areas: health, agriculture and food, low carbon fuels, chemicals and materials, and waste and environment. Key findings from this survey include “The majority of respondents felt comfortable with using new and emerging technologies on a day-to-day basis, but relatively few could explain what engineering biology is,” “There was a strong belief amongst respondents that applications of engineering biology could be useful. Similarly, the majority were comfortable with each of the specific applications and believe that they will be positive for society,” “There was broad agreement that the government is well placed to make decisions about the use of engineering biology but the public should also be involved in decision making,” and more.

“CSR Biodefense Scorecard: Winter 2024 Update”

From the Council on Strategic Risks: “In the fall of 2023, we kicked off our Biodefense Scorecard series to help inform the public on the progress and implementation status of past CSR recommendations on reducing biological risks. This update captures several areas of sustained positive action across pathogen early warning, diplomacy, and biomanufacturing.”

“Ignoring the Real Biowarfare Threat”

David Heslop and Joel Keep discuss the potential implications of recent renovations at Sergiev Posad-6 in this piece from the Lowy Institute, writing in part “While much attention has been paid to nuclear arms, Washington and Moscow must also address biological weapons, which both nations claimed to renounce many years ago. The fate of such programs is not only a matter for Russia and the United States, but for global health security at large.”

“Instrumentalising Biological Weapons-Related Allegations: Russia’s Compliance Politics and the Norms Against Biological Weapons”

Una Jakob recently published this working paper with CBWNet discussing Russia’s use of BWC compliance procedures and their effect on norms against BW. Jakob explains in part of the paper’s executive summary, “Seen in this light, the Russian activities may counterintuitively have contributed to strengthening the norms against biological weapons at the discursive level, as no actor has called them into question and as their validity has been reaffirmed repeatedly in the process, including by Russia itself. This stands in contrast, however, to Russia’s policy which may contest biological weapons norms at the action level. This discrepancy between the discursive and practical level and its implications for norm strength merit further theoretical attention. On a policy level, it will be important to increase transparency, counter disinformation, and strengthen the means to demonstrate, verify and enhance confidence in compliance with the BWC. This would also strengthen the possibilities to address biological weapons-related allegations, including those made in bad faith, and help sustain the norms against biological weapons comprehensively and in the long term.”

“Workshop on S&T Developments with Relevance for the CWC and BWC”

Anna Krin and Gunnar Jeremias edited this CBWNet working paper detailing a workshop hosted in June at Hamburg University focused on challenges and opportunities facing biological and chemical arms control. Jeremias explains in the introduction, “Throughout the workshop, four panels delved into key topics: the general concept and application of scientific and technological advice in arms control in general and particularly in chemical and biological arms control; current developments in science and technology that may necessitate attention; potential frameworks for organizing verification under the CWC and the prospects for institution building for S&T advice and verification within the BWC; and the technologies and governance methods that could be employed to enhance the efficacy of arms control measures…The insights gathered during these discussions aim to contribute to the ongoing discourse on arms control, ensuring that both the BWC and CWC remain vital in a landscape marked by rapid scientific change. This compendium encapsulates the collaborative efforts and perspectives of workshop participants, reflecting a shared commitment to advancing arms control in an increasingly complex world.”

“High-Impact, Low-Probability: NATO-EUROPOL Cooperation in Countering the CBRN Terrorist Threat to Europe”

This JCBRN Defence COE report by Mathias Katsuya “…draws on secondary-source research and insights provided by JCBRN Defence COE personnel as well as Europol’s CBRN-E Team Leader. An initial threat assessment is followed by a review of Europol’s CBRN capabilities, centring on the role of its European Counter-Terrorism Centre and inhouse CBRN-E Team as key nodes in law enforcement information-sharing, capacity-building, and operational coordination. Having identified key doctrinal and capability overlaps with NATO in addition to a stated commitment by Europol’s CBRN-E Team to enhance its civil-military relations, the report outlines a three-pillar approach to deepening connections between NATO and Europol: short-term measures to foster staff-level contacts in both organisations, a formalised relationship between Europol’s CBRN-E Team and NATO’s JCBRN Defence COE, and deeper institutional linkages to effectively confront current and emerging CBRN threats.”

“Hybrid Threats in the CBRN Environment: Challenges and Implications”

This JCBRN Defence COE paper by Paulina Frederike Gogacz discusses hybrid CBRN threats and their use by actors like Russia. Gogacz explains in the paper’s summary that “An analysis of the six strategic enablers outlined in NATO’s Chemical, Biological, Radiological and Nuclear (CBRN) Defence Policy (2022) indicates important steps to ameliorate current defences and prepare NATO and its member states for future hybrid CBRN threats, thereby increasing overall resilience. They include important aspects: robust intelligence-sharing mechanisms to ensure timely and accurate threat information; comprehensive exercises to simulate and prepare for various CBRN scenarios; strong partnerships both within the alliance and with external entities to foster cooperation and resource sharing; effective strategic communication to manage information and public perception; collaborative scientific research to advance technological capabilities and countermeasures; and the resilience of medical infrastructure to ensure a rapid and effective response to CBRN incidents. These steps collectively aim to bolster NATO’s preparedness and adaptability in the face of evolving hybrid CBRN threats.”

“Securing a Strategic Advantage in Biosecurity for NATO”

Max Breet and Lauren Ross recently authored this commentary for RUSI, writing in their summary “NATO should recognise the importance of biosecurity by understanding it as a new domain. This would allow the Alliance to more effectively leverage existing structures to defend itself against hybrid biological threats.”

“The Rise of Mpox in a Post-Smallpox World”

McQuiston et al. recently published this article in Emerging Infectious Diseases: “Reports of mpox are rising in Africa where the disease is endemic and in new countries where the disease has not been previously seen. The 2022 global outbreak of clade II mpox and an ongoing outbreak of the more lethal clade I mpox highlight the pandemic potential for monkeypox virus. Waning population immunity after the cessation of routine immunization for smallpox plays a key role in the changing epidemiologic patterns of mpox. Sustained human-to-human transmission of mpox is occurring widely in the context of insufficient population immunity, fueling genetic mutations that affect the accuracy of some diagnostic tests and that could lead to changing virulence. Additional research should address complex challenges for control of mpox, including improved diagnostics and medical countermeasures. The availability of vaccines should be expanded not only for outbreak response but also for broader routine use for persons in mpox-endemic countries.”

“Confronting Risks of Mirror Life”

Adamala et al. recently published this Science Policy Forum piece, writing in part, “All known life is homochiral. DNA and RNA are made from “right-handed” nucleotides, and proteins are made from “left-handed” amino acids. Driven by curiosity and plausible applications, some researchers had begun work toward creating lifeforms composed entirely of mirror-image biological molecules. Such mirror organisms would constitute a radical departure from known life, and their creation warrants careful consideration. The capability to create mirror life is likely at least a decade away and would require large investments and major technical advances; we thus have an opportunity to consider and preempt risks before they are realized. Here, we draw on an in-depth analysis of current technical barriers, how they might be eroded by technological progress, and what we deem to be unprecedented and largely overlooked risks (1). We call for broader discussion among the global research community, policy-makers, research funders, industry, civil society, and the public to chart an appropriate path forward.”

Bonus: Read Carl Zimmer’s discussion of this warning in The New York Times here.

NEW: OneLab Network Webinar

“Clinical laboratories must be alert for unusual and potentially infectious agents and immediately notify their Laboratory Response Network (LRN) reference laboratory if routine diagnostic testing results in the potential identification of rare and unusual infectious agents that may be used in a bioterrorist attack or other bio-agent incident. This webinar will describe the LRN and highlight the clinical laboratory’s role and responsibilities in initiating contact with their LRN. Join us as we share an example of a response, new tools, and valuable resources to aid in the clinical laboratory’s response.”

This event will take place on December 17 at 12 pm ET. Register for this event here.

NEW: Understanding the Introduction of Pathogens into Humans- Preventing Patient Zero: A Workshop

“The past few decades have seen the emergence of several diseases with drastic public health and economic consequences. Understanding routes of pathogen emergence and transmission is critical to preventing and mitigating disease spillover and amplification. The National Academies Forum on Microbial Threats will host a hybrid public workshop to address gaps in understanding of disease emergence, with a focus on human-animal interaction and laboratory biosafety. The workshop will explore how applications of existing policy structures, emerging technologies, and actionable research can improve biosecurity measures and prevention of future disease emergence.”

This event will take place on January 15 and 16. Learn more and register here.

NEW: Rise of the Zombie Bugs: The Surprising Science of Parasitic Mind-Control

Johns Hopkins APL’s colloquium will feature Mindy Weisberger, author of the upcoming book Rise of the Zombie Bugs: The Surprising Science of Parasitic Mind-Control: “Zombies are all around us—insect zombies, that is. In Rise of the Zombie Bugs, Mindy Weisberger explores the eerie yet fascinating phenomenon of real-life zombification in the insect class and among other invertebrates. Zombifying parasites reproduce by rewriting their victims’ neurochemistry, transforming them into the “walking dead”: armies of cicadas, spiders, and other hosts that helplessly follow a zombifier’s commands, living only to serve the parasite’s needs until death’s sweet release (and often beyond).”

Learn more about this January 31 event here.

How to Avoid Human-Made Pandemics

From the Asia Centre for Health Security: “Studying viruses that could potentially cause outbreaks is one of the most effective ways to reduce the risk of pandemics. However, this type of research—especially when it involves collecting samples from the field and manipulating pathogens—can unintentionally lead to a pandemic if not managed carefully. Dr Lentzos will discuss her findings from the Pathogen Project, which brought together an international taskforce of scientists, biosecurity and public health experts, ethicists, and civil society leaders to seek consensus on this question: Can we agree on ways to manage research that carries pandemic risk as safely, securely and responsibly as possible?”

This event will take place on January 23 at 8 pm (GMT +8:00) via Zoom. RSVP here.

Preparedness in Rural Communities: National and State/Local Perspectives and Plans

From Penn State: “The COVID-19 pandemic and recent hurricanes have thrust the preparedness of rural communities into the national spotlight. At the federal level, the Administration for Strategic Preparedness and Response and the Centers for Disease Control and Prevention have recently released national goals and plans for preparedness of rural communities. The overall objective of this virtual, 2-day mini-symposium is to identify opportunities in public health and agricultural preparedness and response in rural communities. The mini-symposium will focus upon national perspectives on Thursday, January 30 and the state/local perspectives on Friday, January 31. Speakers include representatives of the Administration for Strategic Preparedness and Response, the Department of Homeland Security, US Department of Agriculture, the USA Center for Rural Public Health Preparedness, and state/local leaders.”

This event will take place on January 30 and 31, from 11 am to 2 pm ET each day. Learn more and register here.

Cyberbiosecurity Summit

From Johns Hopkins APL and Bio-ISAC: “Advancements in biomanufacturing and biotechnology drive the science we need to thrive, everything from apples to vaccines. The Cyberbiosecurity Summit 2025 convenes leading experts in biotechnology, biosecurity, and cybersecurity to explore the intersection of these fields and discuss the strategies to create a safe, secure future for us all.”
This event will take place February 25-26 in Laurel, MD. Register here and review the call for sessions here (closes 12/12).

NEW: The Independent Panel Solicits Views and Insights on Pandemic Prevention, and Response Efforts

The Independent Panel for Pandemic Preparedness and Response, co-chaired by HE Ellen Johnson Sirleaf and RH Helen Clark, welcomes you to share your insights and expertise on the status of international and regional pandemic-related reform processes and initiatives, and how progress can be continued and accelerated in the months and years ahead.”

Learn more about this survey and submit by December 20 here.