The Defense Treat Reduction Agency through its collaborative Ruggedized Antibody Program project, has developed a bio-agent detector 1000x more powerful than currently used ELISA methods.
From DVIDS– ” This technology has demonstrated exquisite analytical and clinical sensitivity, as well as a broad dynamic range. The combination of these two technologies will robustly increase the Department of Defense’s diagnostic armamentarium. This could lead to warfighters being able to detect lower levels of the toxin, therefore decreasing false negatives in environmental samples and earlier discovery in the course of clinical intoxication. SdAbs are recombinant ligand binding antibody fragments derived from the unusual structure of native antibodies found in camels and llamas. These unique heavy chain binding elements offer many desirable properties such as their small size (~15 kDa) and thermal stability, which makes them attractive alternatives to conventional monoclonal antibodies.”
Read more here.
(image courtesy of DTRA)