Pandora Report 6.21.15

Changing things up this week, our lead story is a nuclear photo essay. We’ve also got Russian nuclear posturing and a bunch of other stories you may have missed.

Happy Father’s Day to all the dads out there and enjoy the rest of your weekend!

Next Exit, Armageddon: Photos of America’s Nuclear Weapons Legacy

I love a good photo essay, especially those focused on abandoned places—so this is the perfect* combination of that and nuclear history. Many times on the blog I’ve made somewhat flippant comments about visiting nuclear sites on summer vacation. However, evidently there is great public interest in this. As such, the National Park Service and the Department of Energy will establish the Manhattan Project National Historical Park that will include sites as Los Alamos, Oak Ridge and Hanford.

VICE News—“Elsewhere in the US, the ruins of the Manhattan Project and the arms race that followed remain overlooked. In North Dakota, a pyramid-like anti-missile radar that was built to detect an incoming nuclear attack from the Soviet Union pokes through the prairie grass behind an open fence. In Arizona, a satellite calibration target that was used during the Cold War to help American satellites focus their lenses before spying on the Soviet Union sits covered in weeds near a Motel 6 parking lot. And in a suburban Chicago park, where visitors jog and bird watch, nuclear waste from the world’s first reactor — developed by Italian physicist Enrico Fermi for the Manhattan Project in 1942 — sits buried beneath a sign that reads ‘Caution — Do Not Dig.’”

*Check out the photos. They’re truly extraordinary.

Putin: Russia to Boost Nuclear Arsenal with 40 Missiles

Everything old is new again, it seems. This week Vladimir Putin announced that Russia will put more than 40 new intercontinental ballistic missiles into service in 2015. It is said that the new missiles are part of a military modernization program. However, the announcement comes on the heels of a US proposal to increase its own military presence in NATO states in Eastern Europe.

BBC—“Nato Secretary-General Jens Stoltenberg said that the statement from Mr. Putin was “confirming the pattern and behaviour of Russia over a period of time; we have seen Russia is investing more in defence in general and in its nuclear capability in particular”.

He said: “This nuclear sabre-rattling of Russia is unjustified, it’s destabilising and it’s dangerous.” He added that “what Nato now does in the eastern part of the alliance is something that is proportionate, that is defensive and that is fully in line with our international commitments.’”

Stories You May Have Missed

Image Credit: Federal Government of the United States

Pandora Report 2.7.15

Whatta week, right?! Let’s jump right in to the stories. We’ve got the Subway, flu forecasting, American chemical weapons, and stories you may have missed.

Have a great weekend and a safe and healthy week!

A Close Look at the Germs Crawling Around the Subway

Every single day I ride the metro to work, and every single day, the first thing I do when I get to the office is wash my hands. And, really, that’s what everyone should be doing. A research team from the Weill Cornell Medical College spent the summer of 2013 swabbing turnstiles, subway poles, kiosks, benches, and other “human penetrated surfaces” in all 466 NYC subway stations.

Gothamist—“And they found quite a few signs of life—15,152 types of DNA, in fact—nearly half of which they identified as bacteria. Shocking!

[They] did manage to find some scary stuff, with E. coli, Staphylococcus aureus (skin infections, respiratory disease and food poisoning), Bacillus anthracis (anthrax), and even Yersinia pestis, which is associated with the bubonic plague, popping up in some swabs. Nearly all the stations harbored an antibiotic resistant bacteria called Stenotrophomonas maltophilia, one that often causes respiratory infections in hospitals.”

Forecasts May Soon Predict Flu Patterns

What if we could predict the flu like we predict the weather? That is what teams of researchers are looking at; devising and testing methods to predict the start, peak, and end of flu season. How will they do this? By combining data from the present with knowledge of past patterns to project what might happen in the future.

The Boston Globe—“If the CDC had a flu-season preview in hand, the agency could better time messages on use of vaccines and flu-fighting drugs.

Hospitals could plan staffing for patient surges or make sure key personnel are not on vacation when it appears the epidemic will probably peak. Parents could even take flu forecasts into account in scheduling birthday parties and play dates.”

U.S. to Destroy Largest Remaining Chemical Weapons Cache

Syria isn’t the only country working on destruction of its chemical weapons cache. The Pueblo Chemical Depot, in Southern Colorado, will begin neutralization of 2,600 tons of aging mustard agent in March. This action moves towards American compliance with a 1997 treaty that banned all chemical weapons.

USA Today—“‘The start of Pueblo is an enormous step forward to a world free of chemical weapons,” said Paul Walker, who has tracked chemical warfare for more than 20 years, first as a U.S. House of Representatives staffer and currently with Green Cross International, which advocates on issues of security, poverty and the environment.”

Stories You May Have Missed

 

Image Credit: Wikimedia Commons

Pandora Report 5.16.14

There has been a lot on MERS this week as it continued to spread within the U.S. and Europe. The topic was so big that it was even covered on Buzzfeed (the web aggregator mostly known for quizzes and viral videos.) This made me think, “I wonder what sorts of biodefense topics are covered in traditional, mainstream news sources?” So, in celebration of the end of the Spring 2014 semester, this week I bring you just that!


We’ve got the U.S. Military’s defense plan for Zombies, measles and polio as a possible cancer cure, a photo essay about New York’s lost TB ward, and a doctor’s report from the Ebola fields of West Africa. Congrats to our newest graduates and have a wonderful weekend!

The Pentagon Has a Plan to Stop the Zombie Apocalypse. Seriously.

If you’re worried about the zombie apocalypse like I am (and let’s face it, you probably are since you’re here), here is one less thing to worry about. Like many other contingency plans, the Pentagon has one for dealing with the un-dead. Instead of using fictionalized versions of real countries, this scenario strings together a group of seemingly impossible scenarios that could never be mistaken for a real plan including “vegetarian zombies,” “chicken zombies,” and even (yes, this is not a joke) “evil magic zombies.”

Foreign Policy—“‘This plan fulfills fictional contingency planning guidance tasking for U.S. Strategic Command to develop a comprehensive [plan] to undertake military operations to preserve ‘non-zombie’ humans from the threats posed by a zombie horde,” CONOP 8888’s plan summary reads. “Because zombies pose a threat to all non-zombie human life, [Strategic Command] will be prepared to preserve the sanctity of human life and conduct operations in support of any human population — including traditional adversaries.’”

Can Measles or Polio be the Next Cure for Cancer?

Popular science speaks of viruses as something to be avoided, but what if injecting a person with large amounts of virus could actually cure cancer? That’s what researchers at the Mayo Clinic and Duke University Medical Center did when using measles virus to destroy cancer cells. The results? In very small patient trials the researchers saw significant successes including total remission!

Fox News—“This research is all part of a new medical field of oncolytic virotherapy.  The “proof of concept” studies stem from many years of animal research, analyzing how viruses can penetrate certain types of cancer cells.  A typical cancer cell moves very fast and replicates very rapidly.  Therefore, some viruses have an affinity to get into these cells and use them as incubators, so the viruses can multiply at a fast rate, as well.  But once these viruses are attached, the cancer cells essentially explode and release the virus into the body.”

The Mysterious New York City Island You’ve Never Heard Of

Those who have watched the History Channel’s Life After People or read Alan Weisman’s The World Without Us may find this story especially interesting. Photographer Christopher Payne, became aware of North Brother Island—which lies in the East River—and was allowed by the New York City Department of Parks and Recreation to conduct a photo survey of landscape. Used for a variety of purposes until its abandonment in the 1960s, between the 1880s and the 1930s, North Brother Island was the site of Riverside Hospital, where those suffering from infectious disease were treated in isolation.

Slate—“While Payne knew the island’s story, he often had trouble finding physical evidence of its past. “It was very hard for me to find the artifacts I expected to find. They really just didn’t exist. Most of the time you’re looking at the shell of a building, and it’s so far gone you can’t even tell what it was used for. It forced me to look closer, to see graffiti on the walls or to look on the floor,” he said. “A lot of it was detective work. It was like trying to invent a life for something, trying to find a shot or a view that suggested what it used to be.’”

Windsor Doctor Returns Home after Treating Deadly Ebola Outbreak

As the numbers of infected and deaths continue to rise in the Western Africa Ebola outbreak, one of the stories we haven’t heard often is from physicians working there. In this piece for The Windsor Star, Dr. Tim Jagatic, writes about his experience working for three weeks in Conakry, Guinea, as a member of Doctors without Borders.  He writes about the efforts of Doctors Without Borders and the WHO on stopping the spread of the virus as well as providing care for those infected. When not providing medical care, he reported that doctors would perform triage assessments or perform outreach looking for new patient cases.

The Windsor Star—“Jagatic and his fellow physicians would often encounter resistance to their efforts. “We have to work on demystifying the disease,” said Jagatic.“So many people who were infected with it, they were stigmatized. They were banished from their communities, their families, one thing I was really trying to push is that this is really just a virus, like the measles, like the flu, when you get it you treat it, you go home and you’re done. And you’re just like you were beforehand.’”

 

Image Credit: Christopher Payne

Virus or Bacteria?

If you thought quickly determining whether a patient is suffering from a viral or a bacterial infection should be straightforward and easy, you would be wrong. The difficulty in answering this seemingly simple question is what has contributed so heavily to our current war against antibiotic-resistant bacteria. Luckily for all of us, researchers at Duke University are on it. According to a new study, taking a molecular snapshot of gene activity – when infected with a virus, your body activates a specific set of genes, which are entirely different from the set activated to fight a bacterial infection. The entire process currently takes 12 hours, a number which the researchers are hoping to slash to near-instant. The value in immediately determining something as simple as what kingdom the infectious agent belongs to would be a boon in fighting everything from over prescription of antibiotics to emergent pandemics.

Read more on viral signatures here.

(image: Thomas Splettstoesser)

What virologists’ dreams are made of: A total viral catalog

Believe it or not, we have a tremendous deal to learn about viruses. A lot of huge, fundamental questions about viruses remain unanswered –  are they alive or dead? Where did they originate? How many are there? This last question is in some ways the most feasible to answer, and scientists have begun to do so by examining Indian Flying Fox bats. In a new study, scientists at Columbia university took over a thousand samples from the bat species and scoured them for viruses. They turned up 55 viruses, of which a staggering 50 were hitherto undiscovered. Ten of them are in the same family as Nipah. The scientists now hope to take the viruses found from the Indian Flying Foxes and begin a catalog of viruses which infect the remaining 5,484 known species of mammals. Such a resource, while expensive to produce, would be a huge aid in preparing us for future zoonotic outbreaks.

New York Times – “We might be able to take away this element of surprise if we had a catalog of all the viruses lurking in mammals. As soon as a mysterious epidemic broke out, scientists could turn to the catalog to figure out where the virus came from, potentially gaining some crucial clues to the virus’s biology. But few scientists have ventured to build such a catalog, perhaps because there seemed to be such a vast number of viruses to contend with.’No one’s really been addressing this question, even though it seems like such a fundamental one,’ said Simon J. Anthony, an associate research scientist at Columbia University and a researcher at EcoHealth Alliance, a New York-based scientific research organization.”

Read the full article here.

(image: Fritz Geller-Grimm)

A virus by any other name?

Naming new viruses is a surprisingly tricky, often hotly-contested process, and choosing a name for emergent viruses often has significant ramifications. For instance, the original misnomer of the 2009 H1N1 pandemic – swine flu – resulted in millions of dollars of losses for the American pork industry.  Other, equally unhelpful names for the virus included “Mexican flu”.

Read more in this interesting piece in Pacific Standard Magazine on the long and often circuitous process of virus naming.

Excerpt: “Human disease is littered with examples of fractious, sometimes furious rows over what emerging pathogens are called. Some 30 years ago, when the human immunodeficiency virus, or HIV, was discovered, it was named “GRID,” or “gay-related immune deficiency,” helping to spread the slur ‘the gay plague’. It was not until it became clear the sexually transmitted virus was also infecting heterosexuals and haemophiliacs, that GRID was replaced with the more accurate HIV. More recently, the scientific ‘H1N1’ was the name that stuck for the pandemic flu strain that swept the world in 2009/2010 after earlier suggestions proved too sensitive. An Israeli health minister objected to ‘swine flu’ on religious grounds and ‘Mexican flu’ caused offense to a nation.”