Welcome to this week’s Pandora Report! This issue highlights Anthony Fauci’s contentious Senate hearing on the nation’s COVID-19 response, the state of U.S. public health preparedness as infectious disease threats continue to rise, ongoing H5N1 and New World screwworm challenges, and evolving biosecurity policies at home and abroad.
Anthony Fauci Pleads the Fifth During Contentious Senate COVID-19 Hearing
Former top US health official Anthony Fauci invoked his Fifth Amendment right against self-incrimination during a tense July 29 hearing before the Senate Committee on Homeland Security, declining to answer questions related to the origins of COVID-19 and the nation’s handling of the pandemic. The hearing, led by Committee Chairman Sen. Rand Paul (R-KY), followed the public release of Fauci’s COVID-era diaries and focused on allegations that federal funding supported risky viral research at the Wuhan Institute of Virology. Fauci’s attorneys advised him not to testify, citing ongoing legal concerns despite the presidential pardon he received from former President Joe Biden. Republican senators criticized his refusal to answer questions and raised the possibility of contempt proceedings, while Democratic lawmakers characterized the hearing as politically motivated and defended Fauci’s public health record.
Is America Becoming Less Prepared for the Next Pandemic?
By Carmen Shaw, Pandora Report Managing Editor
The United States is confronting several infectious disease threats at once – hantavirus, screwworm, Ebola, cyclospora, measles, whooping cough, and bird flu. Former CDC officials warn that major changes made by the administration to the nation’s public health infrastructure – reducing funding, cutting staff, changing priorities, and shuttering USAID – have left the US in worse shape than before the COVID-19 pandemic. According to The Guardian, 80% of senior leadership positions at the CDC still lack permanent officials, and the agency has lost an estimated 25-30% of its workforce. Given the dearth of proper “boots on the ground” experience, the US appears less prepared for the next major public health emergency.
It has also been reported that the Trump administration has quietly reduced the role of the HHS’ Agency for Healthcare Research and Quality (AHRQ), which supports research aimed at improving patient safety, healthcare quality, and emergency preparedness. Meanwhile, Politico reported that the State Department will move forward with dispensing approximately $600M in previously delayed vaccine funding after HHS Secretary Robert F. Kennedy Jr. held up the funding for months due to concerns about vaccine safety. Separately, a new analysis found that while the U.S. has strengthened several aspects of its Ebola response since the 2014-2016 West Africa epidemic – including airport screening, lab diagnostics, and hospital preparedness – experts warn that maintaining these capabilities will require sustained investment and experienced personnel.
These concerns surrounding the U.S. international disease response capacity grow as disease activity continues to rise nationwide. U.S. cyclospora infection cases have reached record levels in 2026 following multiple foodborne outbreaks. U.S. measles cases have surpassed last year’s total and reached their highest level in more than three decades, driven by declining childhood vaccination coverage and several outbreaks around the nation. Taken together, these developments paint a troubling picture for the US – even as disease threats continue to mount, the nation’s public health infrastructure appears to be backsliding.
California Judge Rules H5N1 Quarantine Locations to Stay Confidential
By Margeaux Malone, Pandora Report Associate Editor
A Sacramento County Superior Court judge ruled against disclosing the names and locations of California dairies quarantined during the 2024-25 bird flu outbreak, siding with state agriculture officials. More than 750 dairies were quarantined statewide during that period as officials worked to contain the spread of highly pathogenic avian influenza. The suit was filed by the California Rural Legal Assistance (CRLA), which argued that making the information public would improve oversight of the state’s response, help protect dairy workers, and provide researchers with data to better understand the outbreak. The judge acknowledged the public interest in government transparency but concluded that protecting producer confidentiality would encourage farmers to report sick animals promptly and cooperate with disease investigations. Amanda Murray, California’s acting state veterinarian and branch chief of Animal Health and Food Safety Services, wrote, “Loss of this trust would likely have a chilling effect, wherein producers would either delay reporting or not report clinical signs of disease.” Out of fear of public backlash, some farms might have culled sick animals and disposed of them themselves, potentially spreading the disease unintentionally. Industry groups have praised the decision as vital to maintaining trust between producers and regulators, while CRLA says it’s weighing further legal options.
Cattle Imports from Mexico to Resume Amid Ongoing NWS Outbreaks
Last Friday, USDA announced a phased reopening of the US-Mexico border to cattle imports, despite the ongoing efforts to prevent further spread of New World Screwworm (NWS) into the country. Imports will start August 24 at the Douglas, Arizona port, with New Mexico crossings to follow pending Mexico’s compliance with a joint action plan targeting NWS. Sonora and Chihuahua were identified as lower-risk source states in Mexico due to stronger inspection infrastructure. The decision follows sustained pressure from Republicans and cattle industry groups to reopen the border amid elevated beef prices, a concern shared by the administration, which aims to lower prices ahead of the upcoming midterm elections.
Agriculture Secretary Brooke Rollins had previously resisted reopening the southern border over screwworm concerns, while acknowledging the economic challenges it posed to various sectors of the industry in Texas. The Biden administration first closed the border to cattle imports in late 2024 following detection of NWS in southern Mexico. The Trump administration then temporarily reopened the border from January to May 2025, before closing it again as screwworms moved northward in Mexico. While many industry groups applaud the move, others, including the United States Cattlemen’s Association (USCA), remain wary that reopening risks reintroducing the parasite before containment is complete. USCA President Justin Tupper responded to the decision, saying, “Any effort to lower beef prices must not come at the expense of U.S. cattle herd health. We’ve been encouraged to rebuild the domestic herd; it is of utmost importance, and unnecessary exposure to animal health threats is a risk we do not need to take.”
Further Reading:
- “Bird flu is spreading locally, and Australia faces more wildlife deaths. How bad could it get?,” Donna Lu, The Guardian
- “Seroprevalence of Influenza A(H5N1) Virus in Domestic Cats at Epicenter of Dairy Cattle Outbreaks, California, USA, 2024–2026,” Ian G. Bemis, et al., Emerging Infectious Diseases
- “42 confirmed New World screwworm infestations: Texas tracker and what you need to know,” Texas Public Radio
IN OTHER NEWS
Infectious Disease Outbreaks
- “Ebola Outbreak in Congo Set to Become Second-Largest on Record,” Jason Gale, Bloomberg
- “Uganda declares end to latest Ebola outbreak,” Elias Biryabarema, Reuters
- “Explosive mpox outbreak causes 3,000 cases in Madagascar,” Verity Bowman, The Telegraph
- “Stockpiled Ebola vaccines trigger antibody response against Bundibugyo virus in lab tests,” Sanjukta Mondal, Medical Xpress
- “Rand Paul releases Anthony Fauci’s pandemic-era diary notes. Here’s what they tell us,” Ari Daniel, NPR
Biosecurity Governance and High-Risk Research
- “Trump Administration Releases New Government-Wide Policy to End Dangerous High-Risk Research,” HHS
- “Jay Bhattacharya: How NIH Will End Dangerous Gain-of-Function Research,” Jay Bhattacharya, WSJ
- “AI executives worry about their technologies aiding bioterrorists. How likely is that?” Matt Field, Bulletin of the Atomic Scientists
- “Review of Anthropic’s Unredacted Chemical and Biological Risk Report: Claude Opus 4.6,” Andrew Liu, SecureBio
- “The UK Has a Solid Biological Security Strategy,” Al Mauroni, Nuclear Weapons Substack
- “UK Biological Security Strategy – Implementation Stocktake,” Christopher East, CSR
- “The Director-General (DG) of the OPCW is the head of the Technical Secretariat, the executive arm of the Organisation for the Prohibition of Chemical Weapons.” OPCW
- “Suitability of the National Bio and Agro-Defense Facility’s Design,” Department of Agriculture

Rising Temps, Rising Risks: Infectious Disease in the 2026 El Niño Year
From the Pandemic Center: “Climate variability, including El Niño-driven shifts in temperature and rainfall, is reshaping infectious disease risks by altering the environments where pathogens and vectors thrive. This year is progressing towards a historically severe El Niño event — a naturally occurring climate pattern characterized by the warming of surface waters in the central and eastern Pacific Ocean.
What impact will this compounding climate event have on disease prevalence, and which regions are most vulnerable? In this Pandemic Center webinar, we will convene an expert panel to discuss these questions and more.”
This webinar will take place on July 31 at 12:00 PM ET. Learn more and register here.
Data and Situational Awareness for Medical and Public Health Preparedness and Response: A Workshop Series
From the National Academies: “The Forum on Medical and Public Health Preparedness for Disasters and Emergencies workshop series will explore how medical, public health, emergency management, and critical infrastructure data are collected, integrated, analyzed, and translated into real-time information to support timely, coordinated decision-making before, during, and after disasters and emergencies.”
This workshop series will take place on September 23. Learn more and register here.
Preparing for a Future of AI-Enabled Biology – A Workshop
From the National Academy of Medicine (NAM): “Artificial intelligence (AI) is transforming the life sciences, including how researchers study biology, develop vaccines and treatments, and detect disease outbreaks. While these advances could improve public health and preparedness, they also raise important questions about safety, security, and the possibility of misuse.”
This event will take place on August 11-12. Learn more and register here.
Ninth Session of the Working Group on the Strengthening of the Biological Weapons Convention
From the United Nations Office for Disarmament Affairs (UNODA): “We will convene the Ninth Session of the Working Group on the Strengthening of the Biological Weapons Convention (BWC). Chaired by Ambassador Frederico S. Duque Estrada Meyer of Brazil, the meeting will bring together State Parties, international organizations, academic institutions, and civil society representatives to continue discussions on strengthening the Convention and advancing efforts to address biological threats. Public sessions will be webcast through UN Web TV, and side events are expected throughout the week.
This event will take place from August 17-21 at the Palais des Nations in Geneva, Switzerland. Learn more and register by July 31st here.
Biosecurity Simulation Exercise (BSX 2026): Laboratory Incidents & Deliberate Biothreats
From the Asia Centre for Health Security: “This table-top simulation exercise aims to enhance inter-sectoral and inter-disciplinary preparedness for laboratory biosafety and biosecurity (LBB) and deliberate biothreat events (DBE). Through lectures, discussions, and structured, scenario-driven exercises, participants will explore decision-making to detect, risk-assess, and manage high-consequence biological incidents under conditions of incomplete information and unfolding events. Participants will collaborate in teams, building on expert perspectives to address issues in surveillance, diagnostics, public health response, security assessment, and risk communication.”
This in-person event will take place from August 27-28. Learn more and register here.
Training Course on ‘Biotechnology Innovation and Biosecurity’
From the International Centre for Genetic Engineering and Biotechnology (ICGEB) and the Biological Weapons Convention Implementation Support Unit: “This training focuses on strengthening capacities in biosecurity, biosafety, and biological risk management in the context of rapid advances in biotechnology with an integrated, interdisciplinary approach to manage biothreats at the intersection of humans, animals, plants and the environment. It addresses the governance, technical, and operational dimensions of preventing, detecting, and responding to biological threats, while promoting responsible and peaceful scientific research and innovation in accordance with article X of the Biological Weapons Convention (BWC).”
This in-person event will be held from October 12-16 in New Delhi, India. Learn more and apply here.
Biomanufacturing for Defense & Security Summit
From Diversified Solutions Incorporated (DSI Groups): “This event will bring together senior thought leaders and stakeholders from across DoW, Military Research Labs, Federal Government, Commercial Industry, & Academia to discuss how each are advancing biomanufacturing to enhance national security objectives, produce critical materials for defense applications, and strengthen the overall U.S. bioindustrial manufacturing base. Biomanufacturing is crucial for U.S. national security because it enables domestic production of critical materials, medicines, and defense supplies, reducing reliance on foreign adversaries, which in turn creates resilient supply chains for the military and economy.”
This event will take place from October 27-28 at the National Harbor, MD. Learn more and register here.

WHO Internship Programme
From WHO: “A competent and dynamic health workforce at the heart of each health system is essential to advance global health goals. Countries need a pool of health professionals trained and exposed to the systems and processes in the health sector and who understand how stakeholders interact within the international health arena. WHO’s Internship Programme offers a wide range of opportunities for students and recent graduates to gain insight into the technical and administrative programmes of WHO and enrich their knowledge and experience in various areas, thereby contributing to the advancement of public health.”
Learn more and apply here.
OpenAI Bio Bug Bounty Program
From OpenAI: “As part of our ongoing efforts to strengthen our safeguards for advanced AI capabilities in biology, we’re evolving our GPT‑5.5 Bio Bug Bounty to become an ongoing private program—the OpenAI Bio Bounty Program. The program will remain focused on universal jailbreaks that can defeat our predefined biosafety challenge against OpenAI’s frontier models, starting with GPT‑5.6 and going forward. The reward for a universal jailbreak for the OpenAI Bio Bounty Program has been raised from $25,000 to $50,000 for both GPT‑5.6 and GPT‑5.5. Smaller awards may be granted for partial wins at our discretion.”
Learn more and submit your application here.
Disarmament and non-proliferation of WMD – Training Program
From Asser Institute and OPCW: “By 2026, pressure on the international arms control system has reached a point few experts anticipated would arrive so quickly, driven largely by intense geopolitical fragmentation. There is a critical need for professionals who possess the legal, technical, and diplomatic expertise to navigate these modern complexities. This intensive five-day training provides a comprehensive, practical overview of the international non-proliferation and disarmament framework.”
This program will take place from October 26-30 in The Hague, the Netherlands. Learn more and register here.





